Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity
Abstract There is a growing body of evidence showing the importance of physical activity against civilization-induced metabolic diseases, including type 2 diabetes (T2DM) and obesity. Eccentric contraction, when skeletal muscles generate force by lengthening, is a unique type of skeletal muscle acti...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-09-01
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| Series: | Sports Medicine - Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40798-023-00596-2 |
| _version_ | 1827634207576293376 |
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| author | Gergő Szűcs Márton Pipicz Márton Richárd Szabó Tamás Csont László Török Csaba Csonka |
| author_facet | Gergő Szűcs Márton Pipicz Márton Richárd Szabó Tamás Csont László Török Csaba Csonka |
| author_sort | Gergő Szűcs |
| collection | DOAJ |
| description | Abstract There is a growing body of evidence showing the importance of physical activity against civilization-induced metabolic diseases, including type 2 diabetes (T2DM) and obesity. Eccentric contraction, when skeletal muscles generate force by lengthening, is a unique type of skeletal muscle activity. Eccentric contraction may lead to better power production characteristics of the muscle because eccentric contraction requires less energy and can result in higher tension. Therefore, it is an ideal tool in the rehabilitation program of patients. However, the complex metabolic effect (i.e., fat mass reduction, increased lipid oxidation, improvement in blood lipid profile, and increased insulin sensitivity) of the eccentric contraction alone has scarcely been investigated. This paper aims to review the current literature to provide information on whether eccentric contraction can influence metabolic health and body composition in T2DM or obesity. We also discussed the potential role of myokines in mediating the effects of eccentric exercise. A better understanding of the mechanism of eccentric training and particularly their participation in the regulation of metabolic diseases may widen their possible therapeutic use and, thereby, may support the fight against the leading global risks for mortality in the world. |
| first_indexed | 2024-03-09T15:10:11Z |
| format | Article |
| id | doaj.art-bf4e68ff69044282a61bcd21e59c4932 |
| institution | Directory Open Access Journal |
| issn | 2198-9761 |
| language | English |
| last_indexed | 2024-03-09T15:10:11Z |
| publishDate | 2023-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Sports Medicine - Open |
| spelling | doaj.art-bf4e68ff69044282a61bcd21e59c49322023-11-26T13:26:33ZengSpringerOpenSports Medicine - Open2198-97612023-09-019111710.1186/s40798-023-00596-2Effect of Eccentric Exercise on Metabolic Health in Diabetes and ObesityGergő Szűcs0Márton Pipicz1Márton Richárd Szabó2Tamás Csont3László Török4Csaba Csonka5Metabolic Diseases and Cell Signaling (MEDICS) Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of SzegedMetabolic Diseases and Cell Signaling (MEDICS) Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of SzegedMetabolic Diseases and Cell Signaling (MEDICS) Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of SzegedMetabolic Diseases and Cell Signaling (MEDICS) Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of SzegedDepartment of Traumatology, Albert Szent-Györgyi Medical School, University of SzegedMetabolic Diseases and Cell Signaling (MEDICS) Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of SzegedAbstract There is a growing body of evidence showing the importance of physical activity against civilization-induced metabolic diseases, including type 2 diabetes (T2DM) and obesity. Eccentric contraction, when skeletal muscles generate force by lengthening, is a unique type of skeletal muscle activity. Eccentric contraction may lead to better power production characteristics of the muscle because eccentric contraction requires less energy and can result in higher tension. Therefore, it is an ideal tool in the rehabilitation program of patients. However, the complex metabolic effect (i.e., fat mass reduction, increased lipid oxidation, improvement in blood lipid profile, and increased insulin sensitivity) of the eccentric contraction alone has scarcely been investigated. This paper aims to review the current literature to provide information on whether eccentric contraction can influence metabolic health and body composition in T2DM or obesity. We also discussed the potential role of myokines in mediating the effects of eccentric exercise. A better understanding of the mechanism of eccentric training and particularly their participation in the regulation of metabolic diseases may widen their possible therapeutic use and, thereby, may support the fight against the leading global risks for mortality in the world.https://doi.org/10.1186/s40798-023-00596-2Eccentric trainingLengthening contractionExerciseDownhillPrediabetesInsulin resistance |
| spellingShingle | Gergő Szűcs Márton Pipicz Márton Richárd Szabó Tamás Csont László Török Csaba Csonka Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity Sports Medicine - Open Eccentric training Lengthening contraction Exercise Downhill Prediabetes Insulin resistance |
| title | Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity |
| title_full | Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity |
| title_fullStr | Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity |
| title_full_unstemmed | Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity |
| title_short | Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity |
| title_sort | effect of eccentric exercise on metabolic health in diabetes and obesity |
| topic | Eccentric training Lengthening contraction Exercise Downhill Prediabetes Insulin resistance |
| url | https://doi.org/10.1186/s40798-023-00596-2 |
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