Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants
Cellular heterogeneity can confound functional genomics analyses of bulk tissues. Here, Donovan et al. deconvolute bulk GTEx RNA-seq data utilizing scRNA-seq data from the Tabula Muris project and show the power of using cell populations in eQTL analyses to identify disease and cell-type-associated...
| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artikel |
| Språk: | English |
| Publicerad: |
Nature Portfolio
2020-02-01
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| Serie: | Nature Communications |
| Länkar: | https://doi.org/10.1038/s41467-020-14561-0 |