Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals

Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals

Brain size and cortical folding have increased and decreased recurrently during mammalian evolution. Identifying genetic elements whose sequence or functional properties co-evolve with these traits can provide unique information on evolutionary and developmental mechanisms. A good candidate for such...

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Bibliographic Details
Main Authors: Zane Kliesmete, Lucas Esteban Wange, Beate Vieth, Miriam Esgleas, Jessica Radmer, Matthias Hülsmann, Johanna Geuder, Daniel Richter, Mari Ohnuki, Magdelena Götz, Ines Hellmann, Wolfgang Enard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
mammals
co-evolution
brain size
brain folding
phylogenetics
functional assays
Online Access:https://elifesciences.org/articles/83593

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