CD73-Mediated Formation of Extracellular Adenosine Is Responsible for Adenosine A<sub>2A</sub> Receptor-Mediated Control of Fear Memory and Amygdala Plasticity
Adenosine A<sub>2A</sub> receptors (A<sub>2A</sub>R) control fear memory and the underlying processes of synaptic plasticity in the amygdala. In other brain regions, A<sub>2A</sub>R activation is ensured by ATP-derived extracellular adenosine formed by ecto-5′-nuc...
Main Authors: | Ana Patrícia Simões, Francisco Q. Gonçalves, Daniel Rial, Samira G. Ferreira, João Pedro Lopes, Paula M. Canas, Rodrigo A. Cunha |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/21/12826 |
Similar Items
-
The Ecto-5’-Nucleotidase/CD73 Inhibitor, α,β-Methylene Adenosine 5’-Diphosphate, Exacerbates Carrageenan-Induced Pleurisy in Rat
by: Elisabetta Caiazzo, et al.
Published: (2019-07-01) -
Unraveling the Intricacies of CD73/Adenosine Signaling: The Pulmonary Immune and Stromal Microenvironment in Lung Cancer
by: Maria Saigí, et al.
Published: (2023-12-01) -
Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction
by: Elisabete Augusto, et al.
Published: (2021-09-01) -
Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5′-Nucleotidase (CD73)
by: Elisabetta Caiazzo, et al.
Published: (2020-11-01) -
Low expression of CD39 and CD73 genes in centenarians compared with octogenarians
by: Almudena Crooke, et al.
Published: (2017-05-01)