Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19

Background: Post-COVID Clinics were recommended for patients with persistent symptoms following COVID-19, but no specific tests were suggested for evaluation. This study aimed to present a post-COVID clinic patient cohort and evaluate the use of a post-COVID symptom questionnaire (PCQ) score. Method...

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Main Authors: Jane Agergaard, William M. Ullahammer, Jesper D. Gunst, Lars Østergaard, Berit Schiøttz-Christensen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/24/7338
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author Jane Agergaard
William M. Ullahammer
Jesper D. Gunst
Lars Østergaard
Berit Schiøttz-Christensen
author_facet Jane Agergaard
William M. Ullahammer
Jesper D. Gunst
Lars Østergaard
Berit Schiøttz-Christensen
author_sort Jane Agergaard
collection DOAJ
description Background: Post-COVID Clinics were recommended for patients with persistent symptoms following COVID-19, but no specific tests were suggested for evaluation. This study aimed to present a post-COVID clinic patient cohort and evaluate the use of a post-COVID symptom questionnaire (PCQ) score. Methods: Patients were referred from a population of approximately 1 million citizens. PCQ and standardized health scales were registered. Descriptive analyses were performed to assess the prevalence of symptoms, and correlation analyses was undertaken to asses convergent and discriminant trends between PCQ scores and health scales. Results: Of 547 patients, 447 accepted inclusion. The median age was 47 years and 12% of the patients were hospitalized. At a median of 6.3 (IQR 4.4–9.9) months after the onset of symptoms, 82% of the patients reported both physical exhaustion and concentration difficulties. Functional disability and extreme fatigue were reported as moderate to severe by 33% and 62% of the patients, respectively. The PCQ score correlated significantly with each of the standardized health scales. Conclusion: Patients referred to a Post-COVID Clinic were previously generally healthy. At the time of diagnosis, they reported multiple symptoms with severely affected health. The PCQ score could be used as valid measure of Post-COVID severity.
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spelling doaj.art-bf6aaf61b9f74a7d8e93dcdfc39f183e2023-11-24T15:43:52ZengMDPI AGJournal of Clinical Medicine2077-03832022-12-011124733810.3390/jcm11247338Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19Jane Agergaard0William M. Ullahammer1Jesper D. Gunst2Lars Østergaard3Berit Schiøttz-Christensen4Department of Infectious Diseases, Aarhus University Hospital, 8200 Aarhus, DenmarkDepartment of Infectious Diseases, Aarhus University Hospital, 8200 Aarhus, DenmarkDepartment of Infectious Diseases, Aarhus University Hospital, 8200 Aarhus, DenmarkDepartment of Infectious Diseases, Aarhus University Hospital, 8200 Aarhus, DenmarkDepartment of Infectious Diseases, Aarhus University Hospital, 8200 Aarhus, DenmarkBackground: Post-COVID Clinics were recommended for patients with persistent symptoms following COVID-19, but no specific tests were suggested for evaluation. This study aimed to present a post-COVID clinic patient cohort and evaluate the use of a post-COVID symptom questionnaire (PCQ) score. Methods: Patients were referred from a population of approximately 1 million citizens. PCQ and standardized health scales were registered. Descriptive analyses were performed to assess the prevalence of symptoms, and correlation analyses was undertaken to asses convergent and discriminant trends between PCQ scores and health scales. Results: Of 547 patients, 447 accepted inclusion. The median age was 47 years and 12% of the patients were hospitalized. At a median of 6.3 (IQR 4.4–9.9) months after the onset of symptoms, 82% of the patients reported both physical exhaustion and concentration difficulties. Functional disability and extreme fatigue were reported as moderate to severe by 33% and 62% of the patients, respectively. The PCQ score correlated significantly with each of the standardized health scales. Conclusion: Patients referred to a Post-COVID Clinic were previously generally healthy. At the time of diagnosis, they reported multiple symptoms with severely affected health. The PCQ score could be used as valid measure of Post-COVID severity.https://www.mdpi.com/2077-0383/11/24/7338long COVIDpost-COVID-19 conditionSARS-CoV-2post-COVID clinicpost-COVID symptom questionnaire
spellingShingle Jane Agergaard
William M. Ullahammer
Jesper D. Gunst
Lars Østergaard
Berit Schiøttz-Christensen
Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19
Journal of Clinical Medicine
long COVID
post-COVID-19 condition
SARS-CoV-2
post-COVID clinic
post-COVID symptom questionnaire
title Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19
title_full Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19
title_fullStr Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19
title_full_unstemmed Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19
title_short Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19
title_sort characteristics of a danish post covid cohort referred for examination due to persistent symptoms six months after mild acute covid 19
topic long COVID
post-COVID-19 condition
SARS-CoV-2
post-COVID clinic
post-COVID symptom questionnaire
url https://www.mdpi.com/2077-0383/11/24/7338
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