Hepatoprotective Actions of Ascorbic Acid, Alpha Lipoic Acid and Silymarin or Their Combination Against Acetaminophen-Induced Hepatotoxicity in Rats

Hepatoprotective Actions of Ascorbic Acid, Alpha Lipoic Acid and Silymarin or Their Combination Against Acetaminophen-Induced Hepatotoxicity in Rats

<i>Background and objectives:</i> Ascorbic acid, alpha lipoic acid (ALA) and silymarin are well-known antioxidants that have hepatoprotective effects. This study aims to investigate the effects of these three compounds combined with attenuating drug-induced oxidative stress and cellular...

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Bibliographic Details
Main Authors: Anmar M. Abdulrazzaq, Mujtaba Badr, Omar Gammoh, Asad A. Abu Khalil, Bayan Y. Ghanim, Tawfiq M. Alhussainy, Nidal A. Qinna
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Medicina
Subjects:
acetaminophen
ascorbic acid
silymarin
hepatoprotection
hepatotoxicity
hepatocytes
oxidative stress
Online Access:https://www.mdpi.com/1010-660X/55/5/181

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