Interactions between COVID-19 infection and diabetes
Coronavirus disease 2019 (COVID-19) caused a major pandemic affecting human health and economy around the world since the beginning of 2020. The virus responsible for the disease is “severe acute respiratory syndrome coronavirus 2” (SARS-CoV-2). It invades the target cells by binding to angiotensin-...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1306290/full |
| _version_ | 1797353905781211136 |
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| author | Hassan M. Heshmati |
| author_facet | Hassan M. Heshmati |
| author_sort | Hassan M. Heshmati |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19) caused a major pandemic affecting human health and economy around the world since the beginning of 2020. The virus responsible for the disease is “severe acute respiratory syndrome coronavirus 2” (SARS-CoV-2). It invades the target cells by binding to angiotensin-converting enzyme 2 (ACE2). ACE2 is expressed in several organs including endocrine glands. Multiple endocrine and metabolic systems including the endocrine pancreas have been impacted by COVID-19 infection/pandemic. COVID-19 pandemic can promote obesity through alterations in lifestyle (e.g., unhealthy diet and reduced physical activity due to confinement and isolation) leading to type 2 diabetes and/or can directly impair the function of the endocrine pancreas particularly through a cytokine storm, promoting or aggravating type 1 or type 2 diabetes. The increased ACE2 receptors of high adiposity commonly associated with type 2 diabetes and the chronic hyperglycemia of diabetes with its negative impact on the immune system can increase the risk of COVID-19 infection and its morbidity/mortality. In conclusion, there are bidirectional interactions between COVID-19 pandemic and diabetes (e.g., COVID-19 infection can impact diabetes and diabetes can impact COVID-19 infection). The services offered by healthcare systems for the management of diabetes have been adapted accordingly. |
| first_indexed | 2024-03-08T13:37:41Z |
| format | Article |
| id | doaj.art-bf6f7fefc851487ba6fd2f477296e7a2 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-08T13:37:41Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-bf6f7fefc851487ba6fd2f477296e7a22024-01-16T14:46:09ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922024-01-011410.3389/fendo.2023.13062901306290Interactions between COVID-19 infection and diabetesHassan M. HeshmatiCoronavirus disease 2019 (COVID-19) caused a major pandemic affecting human health and economy around the world since the beginning of 2020. The virus responsible for the disease is “severe acute respiratory syndrome coronavirus 2” (SARS-CoV-2). It invades the target cells by binding to angiotensin-converting enzyme 2 (ACE2). ACE2 is expressed in several organs including endocrine glands. Multiple endocrine and metabolic systems including the endocrine pancreas have been impacted by COVID-19 infection/pandemic. COVID-19 pandemic can promote obesity through alterations in lifestyle (e.g., unhealthy diet and reduced physical activity due to confinement and isolation) leading to type 2 diabetes and/or can directly impair the function of the endocrine pancreas particularly through a cytokine storm, promoting or aggravating type 1 or type 2 diabetes. The increased ACE2 receptors of high adiposity commonly associated with type 2 diabetes and the chronic hyperglycemia of diabetes with its negative impact on the immune system can increase the risk of COVID-19 infection and its morbidity/mortality. In conclusion, there are bidirectional interactions between COVID-19 pandemic and diabetes (e.g., COVID-19 infection can impact diabetes and diabetes can impact COVID-19 infection). The services offered by healthcare systems for the management of diabetes have been adapted accordingly.https://www.frontiersin.org/articles/10.3389/fendo.2023.1306290/fullcoronavirusangiotensin-converting enzyme 2COVID-19 infectionpandemicdiabetesimmune system |
| spellingShingle | Hassan M. Heshmati Interactions between COVID-19 infection and diabetes Frontiers in Endocrinology coronavirus angiotensin-converting enzyme 2 COVID-19 infection pandemic diabetes immune system |
| title | Interactions between COVID-19 infection and diabetes |
| title_full | Interactions between COVID-19 infection and diabetes |
| title_fullStr | Interactions between COVID-19 infection and diabetes |
| title_full_unstemmed | Interactions between COVID-19 infection and diabetes |
| title_short | Interactions between COVID-19 infection and diabetes |
| title_sort | interactions between covid 19 infection and diabetes |
| topic | coronavirus angiotensin-converting enzyme 2 COVID-19 infection pandemic diabetes immune system |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1306290/full |
| work_keys_str_mv | AT hassanmheshmati interactionsbetweencovid19infectionanddiabetes |