Controversies in the detection of neural autoantibodies

The last 15 years has seen the discovery of treatable antibody-mediated CNS diseases. The accurate detection of specific antibodies helps support patient diagnosis, treatment and predict prognosis. Here we discuss some of the limitations of different antibody detection technologies, caveats in study...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Philippa Pettingill, Thashi Chang, Sarosh Irani, Patrick Waters
Format: Artykuł
Język:English
Wydane: Whitehouse Publishing 2016-09-01
Seria:Advances in Clinical Neuroscience & Rehabilitation
Dostęp online:https://acnr.co.uk/articles/controversies-in-the-detection-of-neural-autoantibodies/
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author Philippa Pettingill
Thashi Chang
Sarosh Irani
Patrick Waters
author_facet Philippa Pettingill
Thashi Chang
Sarosh Irani
Patrick Waters
author_sort Philippa Pettingill
collection DOAJ
description The last 15 years has seen the discovery of treatable antibody-mediated CNS diseases. The accurate detection of specific antibodies helps support patient diagnosis, treatment and predict prognosis. Here we discuss some of the limitations of different antibody detection technologies, caveats in study designs that impacts on the interpretation of assays for routine clinical use and highlight a lack of data on serum versus CSF testing in this new field of neuroimmunology.
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spelling doaj.art-bf709de3c1164a0c87fb7fc38b8653292024-03-08T11:51:19ZengWhitehouse PublishingAdvances in Clinical Neuroscience & Rehabilitation1473-93482397-267X2016-09-0110.47795/UFFT4698Controversies in the detection of neural autoantibodiesPhilippa Pettingill0Thashi Chang1Sarosh Irani2Patrick Waters3Postdoctoral Research ScientistConsultant NeurologistConsulant NeurologistPostdoctoral Research ScientistThe last 15 years has seen the discovery of treatable antibody-mediated CNS diseases. The accurate detection of specific antibodies helps support patient diagnosis, treatment and predict prognosis. Here we discuss some of the limitations of different antibody detection technologies, caveats in study designs that impacts on the interpretation of assays for routine clinical use and highlight a lack of data on serum versus CSF testing in this new field of neuroimmunology.https://acnr.co.uk/articles/controversies-in-the-detection-of-neural-autoantibodies/
spellingShingle Philippa Pettingill
Thashi Chang
Sarosh Irani
Patrick Waters
Controversies in the detection of neural autoantibodies
Advances in Clinical Neuroscience & Rehabilitation
title Controversies in the detection of neural autoantibodies
title_full Controversies in the detection of neural autoantibodies
title_fullStr Controversies in the detection of neural autoantibodies
title_full_unstemmed Controversies in the detection of neural autoantibodies
title_short Controversies in the detection of neural autoantibodies
title_sort controversies in the detection of neural autoantibodies
url https://acnr.co.uk/articles/controversies-in-the-detection-of-neural-autoantibodies/
work_keys_str_mv AT philippapettingill controversiesinthedetectionofneuralautoantibodies
AT thashichang controversiesinthedetectionofneuralautoantibodies
AT saroshirani controversiesinthedetectionofneuralautoantibodies
AT patrickwaters controversiesinthedetectionofneuralautoantibodies