Controversies in the detection of neural autoantibodies
The last 15 years has seen the discovery of treatable antibody-mediated CNS diseases. The accurate detection of specific antibodies helps support patient diagnosis, treatment and predict prognosis. Here we discuss some of the limitations of different antibody detection technologies, caveats in study...
Główni autorzy: | , , , |
---|---|
Format: | Artykuł |
Język: | English |
Wydane: |
Whitehouse Publishing
2016-09-01
|
Seria: | Advances in Clinical Neuroscience & Rehabilitation |
Dostęp online: | https://acnr.co.uk/articles/controversies-in-the-detection-of-neural-autoantibodies/ |
_version_ | 1827322695518257152 |
---|---|
author | Philippa Pettingill Thashi Chang Sarosh Irani Patrick Waters |
author_facet | Philippa Pettingill Thashi Chang Sarosh Irani Patrick Waters |
author_sort | Philippa Pettingill |
collection | DOAJ |
description | The last 15 years has seen the discovery of treatable antibody-mediated CNS diseases. The accurate detection of specific antibodies helps support patient diagnosis, treatment and predict prognosis. Here we discuss some of the limitations of different antibody detection technologies, caveats in study designs that impacts on the interpretation of assays for routine clinical use and highlight a lack of data on serum versus CSF testing in this new field of neuroimmunology. |
first_indexed | 2024-04-25T01:32:43Z |
format | Article |
id | doaj.art-bf709de3c1164a0c87fb7fc38b865329 |
institution | Directory Open Access Journal |
issn | 1473-9348 2397-267X |
language | English |
last_indexed | 2024-04-25T01:32:43Z |
publishDate | 2016-09-01 |
publisher | Whitehouse Publishing |
record_format | Article |
series | Advances in Clinical Neuroscience & Rehabilitation |
spelling | doaj.art-bf709de3c1164a0c87fb7fc38b8653292024-03-08T11:51:19ZengWhitehouse PublishingAdvances in Clinical Neuroscience & Rehabilitation1473-93482397-267X2016-09-0110.47795/UFFT4698Controversies in the detection of neural autoantibodiesPhilippa Pettingill0Thashi Chang1Sarosh Irani2Patrick Waters3Postdoctoral Research ScientistConsultant NeurologistConsulant NeurologistPostdoctoral Research ScientistThe last 15 years has seen the discovery of treatable antibody-mediated CNS diseases. The accurate detection of specific antibodies helps support patient diagnosis, treatment and predict prognosis. Here we discuss some of the limitations of different antibody detection technologies, caveats in study designs that impacts on the interpretation of assays for routine clinical use and highlight a lack of data on serum versus CSF testing in this new field of neuroimmunology.https://acnr.co.uk/articles/controversies-in-the-detection-of-neural-autoantibodies/ |
spellingShingle | Philippa Pettingill Thashi Chang Sarosh Irani Patrick Waters Controversies in the detection of neural autoantibodies Advances in Clinical Neuroscience & Rehabilitation |
title | Controversies in the detection of neural autoantibodies |
title_full | Controversies in the detection of neural autoantibodies |
title_fullStr | Controversies in the detection of neural autoantibodies |
title_full_unstemmed | Controversies in the detection of neural autoantibodies |
title_short | Controversies in the detection of neural autoantibodies |
title_sort | controversies in the detection of neural autoantibodies |
url | https://acnr.co.uk/articles/controversies-in-the-detection-of-neural-autoantibodies/ |
work_keys_str_mv | AT philippapettingill controversiesinthedetectionofneuralautoantibodies AT thashichang controversiesinthedetectionofneuralautoantibodies AT saroshirani controversiesinthedetectionofneuralautoantibodies AT patrickwaters controversiesinthedetectionofneuralautoantibodies |