Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients
Matrix Gla protein (MGP) is a calcification inhibitor that plays a role in preventing soft tissue calcification and local mineralization of the vascular wall. The present study aimed to assess the expression of MGP in Peripheral Blood Mononuclear Cells (PBMC) in adult patients with CVD pathologies a...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2021-12-01
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| Series: | Türk Biyokimya Dergisi |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tjb-2021-0167 |
| _version_ | 1811237894085410816 |
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| author | Kiselova-Kaneva Yoana Dimitrova Nazifova-Tasinova Neshe Vankova Deyana Nikolova Miglena Pasheva Milena Yotov Yoto Atanasov Atanas Galunska Bistra |
| author_facet | Kiselova-Kaneva Yoana Dimitrova Nazifova-Tasinova Neshe Vankova Deyana Nikolova Miglena Pasheva Milena Yotov Yoto Atanasov Atanas Galunska Bistra |
| author_sort | Kiselova-Kaneva Yoana Dimitrova |
| collection | DOAJ |
| description | Matrix Gla protein (MGP) is a calcification inhibitor that plays a role in preventing soft tissue calcification and local mineralization of the vascular wall. The present study aimed to assess the expression of MGP in Peripheral Blood Mononuclear Cells (PBMC) in adult patients with CVD pathologies and its association with the presence and severity of coronary artery calcium score (CACS) and conventional CVD risk factors. |
| first_indexed | 2024-04-12T12:31:16Z |
| format | Article |
| id | doaj.art-bf73e2d202424df08088454d1af805d0 |
| institution | Directory Open Access Journal |
| issn | 1303-829X |
| language | English |
| last_indexed | 2024-04-12T12:31:16Z |
| publishDate | 2021-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Türk Biyokimya Dergisi |
| spelling | doaj.art-bf73e2d202424df08088454d1af805d02022-12-22T03:33:01ZengDe GruyterTürk Biyokimya Dergisi1303-829X2021-12-0147324725510.1515/tjb-2021-0167Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patientsKiselova-Kaneva Yoana Dimitrova0Nazifova-Tasinova Neshe1Vankova Deyana2Nikolova Miglena3Pasheva Milena4Yotov Yoto5Atanasov Atanas6Galunska Bistra7Department of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna, BulgariaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna, BulgariaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna, BulgariaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna, BulgariaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna, BulgariaFirst Department of Internal Diseases, Faculty of Medicine, Medical University of Varna, Varna, BulgariaFirst Department of Internal Diseases, Faculty of Medicine, Medical University of Varna, Varna, BulgariaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna, BulgariaMatrix Gla protein (MGP) is a calcification inhibitor that plays a role in preventing soft tissue calcification and local mineralization of the vascular wall. The present study aimed to assess the expression of MGP in Peripheral Blood Mononuclear Cells (PBMC) in adult patients with CVD pathologies and its association with the presence and severity of coronary artery calcium score (CACS) and conventional CVD risk factors.https://doi.org/10.1515/tjb-2021-0167biomarkerscardiovascular diseasegene expressionmatrix gla-proteinperipheral blood mononuclear cellsbiyobelirteçlerkardiyovasküler hastalıkmatrix gla-proteinigen ekspresyonuperiferik kan mononükleer hücreleri |
| spellingShingle | Kiselova-Kaneva Yoana Dimitrova Nazifova-Tasinova Neshe Vankova Deyana Nikolova Miglena Pasheva Milena Yotov Yoto Atanasov Atanas Galunska Bistra Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients Türk Biyokimya Dergisi biomarkers cardiovascular disease gene expression matrix gla-protein peripheral blood mononuclear cells biyobelirteçler kardiyovasküler hastalık matrix gla-proteini gen ekspresyonu periferik kan mononükleer hücreleri |
| title | Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients |
| title_full | Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients |
| title_fullStr | Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients |
| title_full_unstemmed | Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients |
| title_short | Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients |
| title_sort | matrix gla protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients |
| topic | biomarkers cardiovascular disease gene expression matrix gla-protein peripheral blood mononuclear cells biyobelirteçler kardiyovasküler hastalık matrix gla-proteini gen ekspresyonu periferik kan mononükleer hücreleri |
| url | https://doi.org/10.1515/tjb-2021-0167 |
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