A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke
This study investigated the time-dependent characteristics of acupuncture and analyzed the association between acupuncture utilization and mortality rates, readmission rates, and complications among ischemic stroke patients. Data from the National Health Insurance Service-National Sample Cohort 2.0...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/10/5/756 |
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| author | Sung-Ryul Choi Eun-San Kim Bo-Hyoung Jang Boyoung Jung In-Hyuk Ha |
| author_facet | Sung-Ryul Choi Eun-San Kim Bo-Hyoung Jang Boyoung Jung In-Hyuk Ha |
| author_sort | Sung-Ryul Choi |
| collection | DOAJ |
| description | This study investigated the time-dependent characteristics of acupuncture and analyzed the association between acupuncture utilization and mortality rates, readmission rates, and complications among ischemic stroke patients. Data from the National Health Insurance Service-National Sample Cohort 2.0 from South Korea were used to track patients with subacute and chronic ischemic stroke, who had survived more than one month after onset, between 2010 and 2013. A total of 2299 patients were followed up until 2015. At baseline, the acupuncture group (<i>n</i> = 195) and the control group (<i>n</i> = 2104) had similar ages (acupuncture group: 69.0 ± 11.1 years; control group: 68.5 ± 11.8 years), but the acupuncture group had more comorbidities (Charlson comorbidity index; acupuncture group: 4.7 ± 2.1, control group: 4.3 ± 2.4). According to time-dependent Cox regression survival analysis, acupuncture treatment was associated with low hazard ratios (HR) for death (HR: 0.32; 95% confidence interval (CI): 0.18–0.60), fewer composite complications (HR: 0.34; 95% CI: 0.21–0.53), and reduced urinary tract infection (HR: 0.24; 95% CI: 0.11–0.54). Many acupuncture session sensitivity analyses were performed to assess the robustness using different criteria to define the acupuncture group, and the results were consistent with those of the main analysis. Therefore, acupuncture treatment might be associated with lower mortality rates and the prevention of complications after ischemic stroke. |
| first_indexed | 2024-03-10T03:49:37Z |
| format | Article |
| id | doaj.art-bf73ebc7a61f449384ec22a53706e14c |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-10T03:49:37Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-bf73ebc7a61f449384ec22a53706e14c2023-11-23T11:12:32ZengMDPI AGHealthcare2227-90322022-04-0110575610.3390/healthcare10050756A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic StrokeSung-Ryul Choi0Eun-San Kim1Bo-Hyoung Jang2Boyoung Jung3In-Hyuk Ha4Jaseng Hospital of Korean Medicine, Seoul 06110, KoreaJaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 06110, KoreaDepartment of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, KoreaDepartment of Health Administration, Hanyang Women’s University, Seoul 04763, KoreaJaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 06110, KoreaThis study investigated the time-dependent characteristics of acupuncture and analyzed the association between acupuncture utilization and mortality rates, readmission rates, and complications among ischemic stroke patients. Data from the National Health Insurance Service-National Sample Cohort 2.0 from South Korea were used to track patients with subacute and chronic ischemic stroke, who had survived more than one month after onset, between 2010 and 2013. A total of 2299 patients were followed up until 2015. At baseline, the acupuncture group (<i>n</i> = 195) and the control group (<i>n</i> = 2104) had similar ages (acupuncture group: 69.0 ± 11.1 years; control group: 68.5 ± 11.8 years), but the acupuncture group had more comorbidities (Charlson comorbidity index; acupuncture group: 4.7 ± 2.1, control group: 4.3 ± 2.4). According to time-dependent Cox regression survival analysis, acupuncture treatment was associated with low hazard ratios (HR) for death (HR: 0.32; 95% confidence interval (CI): 0.18–0.60), fewer composite complications (HR: 0.34; 95% CI: 0.21–0.53), and reduced urinary tract infection (HR: 0.24; 95% CI: 0.11–0.54). Many acupuncture session sensitivity analyses were performed to assess the robustness using different criteria to define the acupuncture group, and the results were consistent with those of the main analysis. Therefore, acupuncture treatment might be associated with lower mortality rates and the prevention of complications after ischemic stroke.https://www.mdpi.com/2227-9032/10/5/756acupunctureischemic strokemortalitycomplicationstime-dependent analysis |
| spellingShingle | Sung-Ryul Choi Eun-San Kim Bo-Hyoung Jang Boyoung Jung In-Hyuk Ha A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke Healthcare acupuncture ischemic stroke mortality complications time-dependent analysis |
| title | A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke |
| title_full | A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke |
| title_fullStr | A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke |
| title_full_unstemmed | A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke |
| title_short | A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke |
| title_sort | time dependent analysis of association between acupuncture utilization and the prognosis of ischemic stroke |
| topic | acupuncture ischemic stroke mortality complications time-dependent analysis |
| url | https://www.mdpi.com/2227-9032/10/5/756 |
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