Autophagy-mediated ferroptosis involved in nickel-induced nephrotoxicity in the mice

Autophagy-mediated ferroptosis involved in nickel-induced nephrotoxicity in the mice

Nickel, as a widely polluted metal, has been shown nephrotoxicity. Ferroptosis is a new type of cell death driven by iron-dependent lipid peroxidation. Our study found that nickel chloride (NiCl2) induced ferroptosis in mouse kidney and TCMK-1 cells. The iron content was significantly increased in t...

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Bibliographic Details
Main Authors: Qing Yang, Zhicai Zuo, Yuxin Zeng, Yujuan Ouyang, Hengmin Cui, Huidan Deng, Yanqiu Zhu, Junliang Deng, Yi Geng, Ping Ouyang, Weiming Lai, Zongjun Du, Xueqin Ni, Heng Yin, Jing Fang, Hongrui Guo
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Nickel
Ferroptosis
Autophagy
Kidney
TCMK-1
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323005535

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