Dehydroabietic acid chemosensitizes drug-resistant acute lymphoblastic leukemia cells by downregulating survivin expression

Dehydroabietic acid chemosensitizes drug-resistant acute lymphoblastic leukemia cells by downregulating survivin expression

Objective: To explore the mechanism of drug resistance in acute lymphoblastic leukemia and the anti-tumor effect of combination therapy of dehydroabietic acid and vincristine against acute lymphoblastic leukemia cells. Methods: Acute lymphoblastic leukemia cells REH and CCRF- CEM were employed to de...

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Bibliographic Details
Main Authors:	Li-Li Shen, Wei-Hua Huang, Hui-Jun Zhao, Xue-Wei Yuan
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2022-01-01
Series:	Asian Pacific Journal of Tropical Biomedicine
Subjects:	acute lymphoblastic leukemia; drug resistance; survivin; dehydroabietic acid; reh cells; vincristine
Online Access:	http://www.apjtb.org/article.asp?issn=2221-1691;year=2022;volume=12;issue=9;spage=383;epage=390;aulast=Shen

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