Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remain...

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Bibliographic Details
Main Authors: Alexander C. Aichelburg, Julia Walochnik, Ojan Assadian, Helmut Prosch, Andrea Steuer, Gedeon Perneczky, Govinda S. Visvesvara, Horst Aspöck, Norbert Vetter
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2008-11-01
Series:Emerging Infectious Diseases
Subjects:
Acanthamoeba
granulomatous Acanthamoeba encephalitis (GAE)
tuberculosis
immunocompromised non–HIV-infected patient
miltefosine
dispatch
Online Access:https://wwwnc.cdc.gov/eid/article/14/11/07-0854_article
Description
Summary:We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no signs of infection 2 years after treatment cessation.
ISSN:1080-6040
1080-6059

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