Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine
We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remain...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2008-11-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/14/11/07-0854_article |
| _version_ | 1811213724200992768 |
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| author | Alexander C. Aichelburg Julia Walochnik Ojan Assadian Helmut Prosch Andrea Steuer Gedeon Perneczky Govinda S. Visvesvara Horst Aspöck Norbert Vetter |
| author_facet | Alexander C. Aichelburg Julia Walochnik Ojan Assadian Helmut Prosch Andrea Steuer Gedeon Perneczky Govinda S. Visvesvara Horst Aspöck Norbert Vetter |
| author_sort | Alexander C. Aichelburg |
| collection | DOAJ |
| description | We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no signs of infection 2 years after treatment cessation. |
| first_indexed | 2024-04-12T05:50:56Z |
| format | Article |
| id | doaj.art-bf7b2d795d014b19952c76bd9dc20c02 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-12T05:50:56Z |
| publishDate | 2008-11-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-bf7b2d795d014b19952c76bd9dc20c022022-12-22T03:45:18ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592008-11-0114111743174610.3201/eid1411.070854Successful Treatment of Disseminated Acanthamoeba sp. Infection with MiltefosineAlexander C. AichelburgJulia WalochnikOjan AssadianHelmut ProschAndrea SteuerGedeon PerneczkyGovinda S. VisvesvaraHorst AspöckNorbert VetterWe report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no signs of infection 2 years after treatment cessation.https://wwwnc.cdc.gov/eid/article/14/11/07-0854_articleAcanthamoebagranulomatous Acanthamoeba encephalitis (GAE)tuberculosisimmunocompromised non–HIV-infected patientmiltefosinedispatch |
| spellingShingle | Alexander C. Aichelburg Julia Walochnik Ojan Assadian Helmut Prosch Andrea Steuer Gedeon Perneczky Govinda S. Visvesvara Horst Aspöck Norbert Vetter Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine Emerging Infectious Diseases Acanthamoeba granulomatous Acanthamoeba encephalitis (GAE) tuberculosis immunocompromised non–HIV-infected patient miltefosine dispatch |
| title | Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine |
| title_full | Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine |
| title_fullStr | Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine |
| title_full_unstemmed | Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine |
| title_short | Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine |
| title_sort | successful treatment of disseminated acanthamoeba sp infection with miltefosine |
| topic | Acanthamoeba granulomatous Acanthamoeba encephalitis (GAE) tuberculosis immunocompromised non–HIV-infected patient miltefosine dispatch |
| url | https://wwwnc.cdc.gov/eid/article/14/11/07-0854_article |
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