SARS-CoV-2-reactive IFN-γ-producing CD4+ and CD8+ T cells in blood do not correlate with clinical severity in unvaccinated critically ill COVID-19 patients

SARS-CoV-2-reactive IFN-γ-producing CD4+ and CD8+ T cells in blood do not correlate with clinical severity in unvaccinated critically ill COVID-19 patients

Abstract We examined the relationship between peripheral blood levels of SARS-CoV-2 S (Spike protein)1/M (Membrane protein)-reactive IFN-γ-producing CD4+ and CD8+ T cells, serum levels of biomarkers of clinical severity, and mortality in critically ill COVID-19 patients. The potential association be...

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Bibliographic Details
Main Authors: Beatriz Olea, Eliseo Albert, Estela Giménez, Ignacio Torres, Paula Amat, María José Remigia, Juan Alberola, Nieves Carbonell, José Ferreres, María Luisa Blasco, David Navarro
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18659-x

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https://doi.org/10.1038/s41598-022-18659-x

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