Chronic Inflammation Disrupts Circadian Rhythms in Splenic CD4+ and CD8+ T Cells in Mice

Chronic Inflammation Disrupts Circadian Rhythms in Splenic CD4+ and CD8+ T Cells in Mice

Internal circadian clocks coordinate 24 h rhythms in behavior and physiology. Many immune functions show daily oscillations, and cellular circadian clocks can impact immune functions and disease outcome. Inflammation may disrupt circadian clocks in peripheral tissues and innate immune cells. However...

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Bibliographic Details
Main Authors: Misa Hirose, Alexei Leliavski, Leonardo Vinícius Monteiro de Assis, Olga Matveeva, Ludmila Skrum, Werner Solbach, Henrik Oster, Isabel Heyde
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cells
Subjects:
CD4<sup>+</sup> T cells
CD8<sup>+</sup> T cells
circadian clock
experimental autoimmune encephalomyelitis (EAE)
inflammation
pertussis toxin (PTx)
Online Access:https://www.mdpi.com/2073-4409/13/2/151

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https://www.mdpi.com/2073-4409/13/2/151

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