Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device
Optical coherence tomography (OCT) has changed the standard of care for diagnosis and management of macular diseases in adults. Current commercially available OCT systems, including handheld OCT for pediatric use, have a relatively narrow field of view (FOV), which has limited the potential applicat...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-07-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.860371/full |
| _version_ | 1817975995359035392 |
|---|---|
| author | Thanh-Tin P. Nguyen Shuibin Ni Shuibin Ni Guangru Liang Guangru Liang Shanjida Khan Shanjida Khan Xiang Wei Xiang Wei Alison Skalet Alison Skalet Alison Skalet Alison Skalet Susan Ostmo Michael F. Chiang Yali Jia Yali Jia David Huang David Huang Yifan Jian Yifan Jian J. Peter Campbell |
| author_facet | Thanh-Tin P. Nguyen Shuibin Ni Shuibin Ni Guangru Liang Guangru Liang Shanjida Khan Shanjida Khan Xiang Wei Xiang Wei Alison Skalet Alison Skalet Alison Skalet Alison Skalet Susan Ostmo Michael F. Chiang Yali Jia Yali Jia David Huang David Huang Yifan Jian Yifan Jian J. Peter Campbell |
| author_sort | Thanh-Tin P. Nguyen |
| collection | DOAJ |
| description | Optical coherence tomography (OCT) has changed the standard of care for diagnosis and management of macular diseases in adults. Current commercially available OCT systems, including handheld OCT for pediatric use, have a relatively narrow field of view (FOV), which has limited the potential application of OCT to retinal diseases with primarily peripheral pathology, including many of the most common pediatric retinal conditions. More broadly, diagnosis of all types of retinal detachment (exudative, tractional, and rhegmatogenous) may be improved with OCT-based assessment of retinal breaks, identification of proliferative vitreoretinopathy (PVR) membranes, and the pattern of subretinal fluid. Intraocular tumors both benign and malignant often occur outside of the central macula and may be associated with exudation, subretinal and intraretinal fluid, and vitreoretinal traction. The development of wider field OCT systems thus has the potential to improve the diagnosis and management of myriad diseases in both adult and pediatric retina. In this paper, we present a case series of pediatric patients with complex vitreoretinal pathology undergoing examinations under anesthesia (EUA) using a portable widefield (WF) swept-source (SS)-OCT device. |
| first_indexed | 2024-04-13T21:56:43Z |
| format | Article |
| id | doaj.art-bf7f27cf076e4a49acebb9152a3d228c |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-13T21:56:43Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-bf7f27cf076e4a49acebb9152a3d228c2022-12-22T02:28:13ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-07-01910.3389/fmed.2022.860371860371Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld DeviceThanh-Tin P. Nguyen0Shuibin Ni1Shuibin Ni2Guangru Liang3Guangru Liang4Shanjida Khan5Shanjida Khan6Xiang Wei7Xiang Wei8Alison Skalet9Alison Skalet10Alison Skalet11Alison Skalet12Susan Ostmo13Michael F. Chiang14Yali Jia15Yali Jia16David Huang17David Huang18Yifan Jian19Yifan Jian20J. Peter Campbell21Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesKnight Cancer Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Radiation Medicine, Oregon Health and Science University, Portland, OR, United StatesDepartment of Dermatology, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesNational Eye Institute, National Institutes of Health, Bethesda, MD, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, OR, United StatesCasey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesOptical coherence tomography (OCT) has changed the standard of care for diagnosis and management of macular diseases in adults. Current commercially available OCT systems, including handheld OCT for pediatric use, have a relatively narrow field of view (FOV), which has limited the potential application of OCT to retinal diseases with primarily peripheral pathology, including many of the most common pediatric retinal conditions. More broadly, diagnosis of all types of retinal detachment (exudative, tractional, and rhegmatogenous) may be improved with OCT-based assessment of retinal breaks, identification of proliferative vitreoretinopathy (PVR) membranes, and the pattern of subretinal fluid. Intraocular tumors both benign and malignant often occur outside of the central macula and may be associated with exudation, subretinal and intraretinal fluid, and vitreoretinal traction. The development of wider field OCT systems thus has the potential to improve the diagnosis and management of myriad diseases in both adult and pediatric retina. In this paper, we present a case series of pediatric patients with complex vitreoretinal pathology undergoing examinations under anesthesia (EUA) using a portable widefield (WF) swept-source (SS)-OCT device.https://www.frontiersin.org/articles/10.3389/fmed.2022.860371/fullretinapediatric retinaoptical coherence tomographyhandheld optical coherence tomographyoptical coherence tomography with angiography |
| spellingShingle | Thanh-Tin P. Nguyen Shuibin Ni Shuibin Ni Guangru Liang Guangru Liang Shanjida Khan Shanjida Khan Xiang Wei Xiang Wei Alison Skalet Alison Skalet Alison Skalet Alison Skalet Susan Ostmo Michael F. Chiang Yali Jia Yali Jia David Huang David Huang Yifan Jian Yifan Jian J. Peter Campbell Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device Frontiers in Medicine retina pediatric retina optical coherence tomography handheld optical coherence tomography optical coherence tomography with angiography |
| title | Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device |
| title_full | Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device |
| title_fullStr | Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device |
| title_full_unstemmed | Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device |
| title_short | Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device |
| title_sort | widefield optical coherence tomography in pediatric retina a case series of intraoperative applications using a prototype handheld device |
| topic | retina pediatric retina optical coherence tomography handheld optical coherence tomography optical coherence tomography with angiography |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.860371/full |
| work_keys_str_mv | AT thanhtinpnguyen widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT shuibinni widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT shuibinni widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT guangruliang widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT guangruliang widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT shanjidakhan widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT shanjidakhan widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT xiangwei widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT xiangwei widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT alisonskalet widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT alisonskalet widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT alisonskalet widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT alisonskalet widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT susanostmo widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT michaelfchiang widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT yalijia widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT yalijia widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT davidhuang widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT davidhuang widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT yifanjian widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT yifanjian widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice AT jpetercampbell widefieldopticalcoherencetomographyinpediatricretinaacaseseriesofintraoperativeapplicationsusingaprototypehandhelddevice |