Functional equivalency inferred from "authoritative sources" in networks of homologous proteins.

A one-on-one mapping of protein functionality across different species is a critical component of comparative analysis. This paper presents a heuristic algorithm for discovering the Most Likely Functional Counterparts (MoLFunCs) of a protein, based on simple concepts from network theory. A key featu...

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Bibliographic Details
Main Authors: Shreedhar Natarajan, Eric Jakobsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2690840?pdf=render

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