Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year history
Based on the data available in the literature, the author has first systematized in detail the main stages of the design and clinical introduction of serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressants. Theoretical prerequisites for their emergence are described. The evaluation of...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2018-12-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
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| Online Access: | https://nnp.ima-press.net/nnp/article/view/990 |
| _version_ | 1827062867244875776 |
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| author | D. S. Danilov |
| author_facet | D. S. Danilov |
| author_sort | D. S. Danilov |
| collection | DOAJ |
| description | Based on the data available in the literature, the author has first systematized in detail the main stages of the design and clinical introduction of serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressants. Theoretical prerequisites for their emergence are described. The evaluation of the efficiency of depression therapy with drugs of this group in clinical trials and post-marketing studies is analyzed in the historical context. The reasons for temporary restrictions on their wide use are considered. There are data on the design of novel representatives of SNRI antidepressants. |
| first_indexed | 2024-04-10T02:02:25Z |
| format | Article |
| id | doaj.art-bf868773f71947cb834a13abc86f207e |
| institution | Directory Open Access Journal |
| issn | 2074-2711 2310-1342 |
| language | Russian |
| last_indexed | 2025-02-18T20:02:42Z |
| publishDate | 2018-12-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Неврология, нейропсихиатрия, психосоматика |
| spelling | doaj.art-bf868773f71947cb834a13abc86f207e2024-10-17T16:15:25ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422018-12-0110441210.14412/2074-2711-2018-4-4-12793Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year historyD. S. Danilov0S.S. Korsakov Clinic of Psychiatry; University Clinical Hospital Three, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaBased on the data available in the literature, the author has first systematized in detail the main stages of the design and clinical introduction of serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressants. Theoretical prerequisites for their emergence are described. The evaluation of the efficiency of depression therapy with drugs of this group in clinical trials and post-marketing studies is analyzed in the historical context. The reasons for temporary restrictions on their wide use are considered. There are data on the design of novel representatives of SNRI antidepressants.https://nnp.ima-press.net/nnp/article/view/990antidepressantsserotonin and norepinephrine reuptake inhibitorsdual-action antidepressantsvenlafaxinemilnacipranduloxe-tinedesvenlafaxinelevomilnacipranclovoxaminesibutraminehistory of psychopharmacologyhistory of psychopharmacotherapy |
| spellingShingle | D. S. Danilov Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year history Неврология, нейропсихиатрия, психосоматика antidepressants serotonin and norepinephrine reuptake inhibitors dual-action antidepressants venlafaxine milnacipran duloxe-tine desvenlafaxine levomilnacipran clovoxamine sibutramine history of psychopharmacology history of psychopharmacotherapy |
| title | Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year history |
| title_full | Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year history |
| title_fullStr | Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year history |
| title_full_unstemmed | Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year history |
| title_short | Serotonin and norepinephrine reuptake inhibitor antidepressants: a look through the prism of their 30-year history |
| title_sort | serotonin and norepinephrine reuptake inhibitor antidepressants a look through the prism of their 30 year history |
| topic | antidepressants serotonin and norepinephrine reuptake inhibitors dual-action antidepressants venlafaxine milnacipran duloxe-tine desvenlafaxine levomilnacipran clovoxamine sibutramine history of psychopharmacology history of psychopharmacotherapy |
| url | https://nnp.ima-press.net/nnp/article/view/990 |
| work_keys_str_mv | AT dsdanilov serotoninandnorepinephrinereuptakeinhibitorantidepressantsalookthroughtheprismoftheir30yearhistory |