Personality traits in the siblings and children of patients with frontotemporal dementia: A questionnaire-based study

Introduction: Frontotemporal dementias (FLD) form a group of relatively young onset, male dominant dementias with significant behavioral abnormalities early in the course of the disease. Routine assessment suggested preexisting traits such as lack of empathy, self-directedness, and persistence in mo...

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Main Authors: Suresh Kumar Korada, Sadanandavalli Retnaswami Chandra, Vivek Benegal, Meera Purushothaman, Mariamma Philip
Format: Article
Language:English
Published: SAGE Publishing 2017-01-01
Series:Indian Journal of Psychological Medicine
Subjects:
Online Access:http://www.ijpm.info/article.asp?issn=0253-7176;year=2017;volume=39;issue=1;spage=28;epage=31;aulast=Korada
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author Suresh Kumar Korada
Sadanandavalli Retnaswami Chandra
Vivek Benegal
Meera Purushothaman
Mariamma Philip
author_facet Suresh Kumar Korada
Sadanandavalli Retnaswami Chandra
Vivek Benegal
Meera Purushothaman
Mariamma Philip
author_sort Suresh Kumar Korada
collection DOAJ
description Introduction: Frontotemporal dementias (FLD) form a group of relatively young onset, male dominant dementias with significant behavioral abnormalities early in the course of the disease. Routine assessment suggested preexisting traits such as lack of empathy, self-directedness, and persistence in most of these persons even before the onset of disease. Hence, we decided the study, the siblings and children of patients for any specific traits and correlation with hexanucleotide expansion repeats if any traits were identified. Patients and Methods: A total of 35 age- and gender-matched cases and controls were included for the study as per criteria. They were screened for mental illness and cognitive dysfunction using Hindi Mental State Examination and Mini-mental State Examination. Eligible persons were given temperament and character inventory (TCI) scores for the recommended parameters. Hexanucleotide expansion was also studied in the patients, cases and controls. Results: No specific personality trait was found to have an increased correlation with siblings and children of patients with FLD in this small group using TCI scores. Conclusions: 7% of cases showed Hexanucleotide expansion suggesting a possible risk.The role of self reporting bias resulting in normal personality trait needs to be addressed in future studies.
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spelling doaj.art-bf869a0883d54a73adde50f8d25571752022-12-21T20:02:19ZengSAGE PublishingIndian Journal of Psychological Medicine0253-71762017-01-01391283110.4103/0253-7176.198943Personality traits in the siblings and children of patients with frontotemporal dementia: A questionnaire-based studySuresh Kumar KoradaSadanandavalli Retnaswami ChandraVivek BenegalMeera PurushothamanMariamma PhilipIntroduction: Frontotemporal dementias (FLD) form a group of relatively young onset, male dominant dementias with significant behavioral abnormalities early in the course of the disease. Routine assessment suggested preexisting traits such as lack of empathy, self-directedness, and persistence in most of these persons even before the onset of disease. Hence, we decided the study, the siblings and children of patients for any specific traits and correlation with hexanucleotide expansion repeats if any traits were identified. Patients and Methods: A total of 35 age- and gender-matched cases and controls were included for the study as per criteria. They were screened for mental illness and cognitive dysfunction using Hindi Mental State Examination and Mini-mental State Examination. Eligible persons were given temperament and character inventory (TCI) scores for the recommended parameters. Hexanucleotide expansion was also studied in the patients, cases and controls. Results: No specific personality trait was found to have an increased correlation with siblings and children of patients with FLD in this small group using TCI scores. Conclusions: 7% of cases showed Hexanucleotide expansion suggesting a possible risk.The role of self reporting bias resulting in normal personality trait needs to be addressed in future studies.http://www.ijpm.info/article.asp?issn=0253-7176;year=2017;volume=39;issue=1;spage=28;epage=31;aulast=KoradaFrontotemporal dementiapersonality traits in close family memberstemperament and character inventory scores
spellingShingle Suresh Kumar Korada
Sadanandavalli Retnaswami Chandra
Vivek Benegal
Meera Purushothaman
Mariamma Philip
Personality traits in the siblings and children of patients with frontotemporal dementia: A questionnaire-based study
Indian Journal of Psychological Medicine
Frontotemporal dementia
personality traits in close family members
temperament and character inventory scores
title Personality traits in the siblings and children of patients with frontotemporal dementia: A questionnaire-based study
title_full Personality traits in the siblings and children of patients with frontotemporal dementia: A questionnaire-based study
title_fullStr Personality traits in the siblings and children of patients with frontotemporal dementia: A questionnaire-based study
title_full_unstemmed Personality traits in the siblings and children of patients with frontotemporal dementia: A questionnaire-based study
title_short Personality traits in the siblings and children of patients with frontotemporal dementia: A questionnaire-based study
title_sort personality traits in the siblings and children of patients with frontotemporal dementia a questionnaire based study
topic Frontotemporal dementia
personality traits in close family members
temperament and character inventory scores
url http://www.ijpm.info/article.asp?issn=0253-7176;year=2017;volume=39;issue=1;spage=28;epage=31;aulast=Korada
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