The antimicrobial peptide Esc(1-21)-1c increases susceptibility of Pseudomonas aeruginosa to conventional antibiotics by decreasing the expression of the MexAB-OprM efflux pump

The antimicrobial peptide Esc(1-21)-1c increases susceptibility of Pseudomonas aeruginosa to conventional antibiotics by decreasing the expression of the MexAB-OprM efflux pump

Introduction: The increase in bacterial strains resistant to conventional antibiotics is an alarming problem for human health and could lead to pandemics in the future. Among bacterial pathogens responsible for a large variety of severe infections there is Pseudomonas aeruginosa. Therefore, there is...

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Bibliographic Details
Main Authors: Carolina Canè, Bruno Casciaro, Angela Di Somma, Maria Rosa Loffredo, Elena Puglisi, Gennaro Battaglia, Marta Mellini, Floriana Cappiello, Giordano Rampioni, Livia Leoni, Angela Amoresano, Angela Duilio, Maria Luisa Mangoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Chemistry
Subjects:
Pseudomonas aeruginosa
antimicrobial peptide
antibiotics
tetracycline
efflux pumps
proteomic
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1271153/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2023.1271153/full

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