Genetic predisposition to febrile convulsions: a preliminary study
The participation of genetic factors in the origin of convulsive disorders is a controversial matter. In an attempt to study the influence of heredity in a selected group of patients, we evaluated 128 subjects that presented febrile febrile convulsions. Of these, 18 (14,3 % of the sample) had at lea...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Academia Brasileira de Neurologia (ABNEURO)
1980-12-01
|
Series: | Arquivos de Neuro-Psiquiatria |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1980000400001&lng=en&tlng=en |
Summary: | The participation of genetic factors in the origin of convulsive disorders is a controversial matter. In an attempt to study the influence of heredity in a selected group of patients, we evaluated 128 subjects that presented febrile febrile convulsions. Of these, 18 (14,3 % of the sample) had at least one relative affected by the same problem. Even though a more definite conclusion depends on sample enlargement and on setting up a control group, pedigree observation suggests the participation of an autosomal dominant gene, with incomplete and probably low penetrance, in the etiology of febrile convulsions. |
---|---|
ISSN: | 1678-4227 |