Genetic predisposition to febrile convulsions: a preliminary study
The participation of genetic factors in the origin of convulsive disorders is a controversial matter. In an attempt to study the influence of heredity in a selected group of patients, we evaluated 128 subjects that presented febrile febrile convulsions. Of these, 18 (14,3 % of the sample) had at lea...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
1980-12-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1980000400001&lng=en&tlng=en |
| _version_ | 1811266300404563968 |
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| author | Cesar Noronha Raffin Roberto Giuoliani Jorge Armbrust-Fgueiredo |
| author_facet | Cesar Noronha Raffin Roberto Giuoliani Jorge Armbrust-Fgueiredo |
| author_sort | Cesar Noronha Raffin |
| collection | DOAJ |
| description | The participation of genetic factors in the origin of convulsive disorders is a controversial matter. In an attempt to study the influence of heredity in a selected group of patients, we evaluated 128 subjects that presented febrile febrile convulsions. Of these, 18 (14,3 % of the sample) had at least one relative affected by the same problem. Even though a more definite conclusion depends on sample enlargement and on setting up a control group, pedigree observation suggests the participation of an autosomal dominant gene, with incomplete and probably low penetrance, in the etiology of febrile convulsions. |
| first_indexed | 2024-04-12T20:40:50Z |
| format | Article |
| id | doaj.art-bf9397d5ccf44b60bbde84d470c10b5d |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-04-12T20:40:50Z |
| publishDate | 1980-12-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-bf9397d5ccf44b60bbde84d470c10b5d2022-12-22T03:17:26ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42271980-12-0138432733010.1590/S0004-282X1980000400001S0004-282X1980000400001Genetic predisposition to febrile convulsions: a preliminary studyCesar Noronha Raffin0Roberto Giuoliani1Jorge Armbrust-Fgueiredo2Universidade de São PauloUniversidade de São PauloUniversidade de São PauloThe participation of genetic factors in the origin of convulsive disorders is a controversial matter. In an attempt to study the influence of heredity in a selected group of patients, we evaluated 128 subjects that presented febrile febrile convulsions. Of these, 18 (14,3 % of the sample) had at least one relative affected by the same problem. Even though a more definite conclusion depends on sample enlargement and on setting up a control group, pedigree observation suggests the participation of an autosomal dominant gene, with incomplete and probably low penetrance, in the etiology of febrile convulsions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1980000400001&lng=en&tlng=en |
| spellingShingle | Cesar Noronha Raffin Roberto Giuoliani Jorge Armbrust-Fgueiredo Genetic predisposition to febrile convulsions: a preliminary study Arquivos de Neuro-Psiquiatria |
| title | Genetic predisposition to febrile convulsions: a preliminary study |
| title_full | Genetic predisposition to febrile convulsions: a preliminary study |
| title_fullStr | Genetic predisposition to febrile convulsions: a preliminary study |
| title_full_unstemmed | Genetic predisposition to febrile convulsions: a preliminary study |
| title_short | Genetic predisposition to febrile convulsions: a preliminary study |
| title_sort | genetic predisposition to febrile convulsions a preliminary study |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1980000400001&lng=en&tlng=en |
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