Association of KCNJ6 rs2070995 and methadone response for pain management in advanced cancer at end-of-life
Abstract Opioids are the therapeutic agents of choice to manage moderate to severe pain in patients with advanced cancer, however the unpredictable inter-individual response to opioid therapy remains a challenge for clinicians. While studies are few, the KCNJ6 gene is a promising target for investig...
Main Authors: | Deniz Ozberk, Alison Haywood, Heidi G. Sutherland, Chieh Yu, Cassie L. Albury, Mathew Zunk, Rani George, Phillip Good, Lyn R. Griffiths, Janet Hardy, Larisa M. Haupt |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-21180-w |
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