Removal of Non-Specifically Bound Proteins Using Rayleigh Waves Generated on ST-Quartz Substrates

Removal of Non-Specifically Bound Proteins Using Rayleigh Waves Generated on ST-Quartz Substrates

Label-free biosensors are plagued by the issue of non-specific protein binding which negatively affects sensing parameters such as sensitivity, selectivity, and limit-of-detection. In the current work, we explore the possibility of using the Rayleigh waves in ST-Quartz devices to efficiently remove...

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Bibliographic Details
Main Authors: Mandek Richardson, Pradipta K. Das, Samuel Morrill, Kamlesh J. Suthar, Subramanian K. R. S. Sankaranarayanan, Venkat R. Bhethanabotla
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Sensors
Subjects:
antibody
antigen
biosensing
non-specific binding
Rayleigh waves
surface acoustic wave (SAW)
Online Access:https://www.mdpi.com/1424-8220/22/11/4096

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