Periodic and Aperiodic EEG Features as Potential Markers of Developmental Dyslexia
Developmental Dyslexia (DD) is a neurobiological condition affecting the ability to read fluently and/or accurately. Analyzing resting-state electroencephalographic (EEG) activity in DD may provide a deeper characterization of the underlying pathophysiology and possible biomarkers. So far, studies i...
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| Format: | Article |
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MDPI AG
2023-06-01
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| Serier: | Biomedicines |
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| Online adgang: | https://www.mdpi.com/2227-9059/11/6/1607 |
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| author | Chiara Turri Giuseppe Di Dona Alessia Santoni Denisa Adina Zamfira Laura Franchin David Melcher Luca Ronconi |
| author_facet | Chiara Turri Giuseppe Di Dona Alessia Santoni Denisa Adina Zamfira Laura Franchin David Melcher Luca Ronconi |
| author_sort | Chiara Turri |
| collection | DOAJ |
| description | Developmental Dyslexia (DD) is a neurobiological condition affecting the ability to read fluently and/or accurately. Analyzing resting-state electroencephalographic (EEG) activity in DD may provide a deeper characterization of the underlying pathophysiology and possible biomarkers. So far, studies investigating resting-state activity in DD provided limited evidence and did not consider the aperiodic component of the power spectrum. In the present study, adults with (<i>n</i> = 26) and without DD (<i>n</i> = 31) underwent a reading skills assessment and resting-state EEG to investigate potential alterations in aperiodic activity, their impact on the periodic counterpart and reading performance. In parieto-occipital channels, DD participants showed a significantly different aperiodic activity as indexed by a flatter and lower power spectrum. These aperiodic measures were significantly related to text reading time, suggesting a link with individual differences in reading difficulties. In the beta band, the DD group showed significantly decreased aperiodic-adjusted power compared to typical readers, which was significantly correlated to word reading accuracy. Overall, here we provide evidence showing alterations of the endogenous aperiodic activity in DD participants consistently with the increased neural noise hypothesis. In addition, we confirm alterations of endogenous beta rhythms, which are discussed in terms of their potential link with magnocellular-dorsal stream deficit. |
| first_indexed | 2024-03-11T02:45:04Z |
| format | Article |
| id | doaj.art-bf9e2610925a412191ce748cae0cd1a5 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-11T02:45:04Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-bf9e2610925a412191ce748cae0cd1a52023-11-18T09:25:41ZengMDPI AGBiomedicines2227-90592023-06-01116160710.3390/biomedicines11061607Periodic and Aperiodic EEG Features as Potential Markers of Developmental DyslexiaChiara Turri0Giuseppe Di Dona1Alessia Santoni2Denisa Adina Zamfira3Laura Franchin4David Melcher5Luca Ronconi6School of Psychology, Vita-Salute San Raffaele University, 20132 Milan, ItalySchool of Psychology, Vita-Salute San Raffaele University, 20132 Milan, ItalySchool of Psychology, Vita-Salute San Raffaele University, 20132 Milan, ItalySchool of Psychology, Vita-Salute San Raffaele University, 20132 Milan, ItalyDepartment of Psychology and Cognitive Science, University of Trento, 38068 Rovereto, ItalyDepartment of Psychology and Cognitive Science, University of Trento, 38068 Rovereto, ItalySchool of Psychology, Vita-Salute San Raffaele University, 20132 Milan, ItalyDevelopmental Dyslexia (DD) is a neurobiological condition affecting the ability to read fluently and/or accurately. Analyzing resting-state electroencephalographic (EEG) activity in DD may provide a deeper characterization of the underlying pathophysiology and possible biomarkers. So far, studies investigating resting-state activity in DD provided limited evidence and did not consider the aperiodic component of the power spectrum. In the present study, adults with (<i>n</i> = 26) and without DD (<i>n</i> = 31) underwent a reading skills assessment and resting-state EEG to investigate potential alterations in aperiodic activity, their impact on the periodic counterpart and reading performance. In parieto-occipital channels, DD participants showed a significantly different aperiodic activity as indexed by a flatter and lower power spectrum. These aperiodic measures were significantly related to text reading time, suggesting a link with individual differences in reading difficulties. In the beta band, the DD group showed significantly decreased aperiodic-adjusted power compared to typical readers, which was significantly correlated to word reading accuracy. Overall, here we provide evidence showing alterations of the endogenous aperiodic activity in DD participants consistently with the increased neural noise hypothesis. In addition, we confirm alterations of endogenous beta rhythms, which are discussed in terms of their potential link with magnocellular-dorsal stream deficit.https://www.mdpi.com/2227-9059/11/6/1607developmental dyslexiareadingreading disorderEEGsignal-to-noise rationeurodevelopmental disorder |
| spellingShingle | Chiara Turri Giuseppe Di Dona Alessia Santoni Denisa Adina Zamfira Laura Franchin David Melcher Luca Ronconi Periodic and Aperiodic EEG Features as Potential Markers of Developmental Dyslexia Biomedicines developmental dyslexia reading reading disorder EEG signal-to-noise ratio neurodevelopmental disorder |
| title | Periodic and Aperiodic EEG Features as Potential Markers of Developmental Dyslexia |
| title_full | Periodic and Aperiodic EEG Features as Potential Markers of Developmental Dyslexia |
| title_fullStr | Periodic and Aperiodic EEG Features as Potential Markers of Developmental Dyslexia |
| title_full_unstemmed | Periodic and Aperiodic EEG Features as Potential Markers of Developmental Dyslexia |
| title_short | Periodic and Aperiodic EEG Features as Potential Markers of Developmental Dyslexia |
| title_sort | periodic and aperiodic eeg features as potential markers of developmental dyslexia |
| topic | developmental dyslexia reading reading disorder EEG signal-to-noise ratio neurodevelopmental disorder |
| url | https://www.mdpi.com/2227-9059/11/6/1607 |
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