Essential Heavy Metals in Renal Tumor Tissue and Its Possible Relation to Carcinogenesis: Applying the Scanning Electron Microscopy Coupled with X-Ray Microanalysis Technique
Background: Metals such as copper and zinc are crucial in several vital functions in the human body; the absence of these metals can cause serious illness. When in excess, however, they can have toxic effects which may be associated with carcinogenesis, as is described in the literature. Thus, it is...
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| Format: | Article |
| Language: | English |
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University Library System, University of Pittsburgh
2015-03-01
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| Series: | International Journal of Medical Students |
| Subjects: | |
| Online Access: | http://www.ijms.info/ojs/index.php/IJMS/article/view/169 |
| _version_ | 1797762967643619328 |
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| author | Tânia Nogueira Mariana Semedo Elisabete Cunha |
| author_facet | Tânia Nogueira Mariana Semedo Elisabete Cunha |
| author_sort | Tânia Nogueira |
| collection | DOAJ |
| description | Background: Metals such as copper and zinc are crucial in several vital functions in the human body; the absence of these metals can cause serious illness. When in excess, however, they can have toxic effects which may be associated with carcinogenesis, as is described in the literature. Thus, it is important to realize that without these essential metals in their due proportion, the human body could not maintain its proper metabolic function.
Methods: The main goal of this paper was to compare qualitatively and semi-quantitatively the amount of both copper and zinc present in the tumor tissue (tissue from patients who had undergone partial or radical nephrectomy) and in the control tissue (which was adjacent to the tumor tissue). This study was carried out using Scanning Electron Microscopy coupled with X-Ray Microanalysis (SEM-XRM).
Results: There is a different concentration of copper and zinc in the samples of tumor tissue and controls that were studied.
Conclusion: This work complements previously published results about the presence of metals in the human body and their probable influence on carcinogenesis. |
| first_indexed | 2024-03-12T19:34:53Z |
| format | Article |
| id | doaj.art-bf9e8822888247dfb2920c2c3a08d48b |
| institution | Directory Open Access Journal |
| issn | 2076-6327 |
| language | English |
| last_indexed | 2024-03-12T19:34:53Z |
| publishDate | 2015-03-01 |
| publisher | University Library System, University of Pittsburgh |
| record_format | Article |
| series | International Journal of Medical Students |
| spelling | doaj.art-bf9e8822888247dfb2920c2c3a08d48b2023-08-02T04:16:04ZengUniversity Library System, University of PittsburghInternational Journal of Medical Students2076-63272015-03-01311014Essential Heavy Metals in Renal Tumor Tissue and Its Possible Relation to Carcinogenesis: Applying the Scanning Electron Microscopy Coupled with X-Ray Microanalysis TechniqueTânia Nogueira0Mariana Semedo1Elisabete Cunha2Universidade de Vigo, Spain.Instituto de Ciências Biomédicas Abel Salazar, Portugal.Faculdade de Medicina da Universidade do Porto, Portugal.Background: Metals such as copper and zinc are crucial in several vital functions in the human body; the absence of these metals can cause serious illness. When in excess, however, they can have toxic effects which may be associated with carcinogenesis, as is described in the literature. Thus, it is important to realize that without these essential metals in their due proportion, the human body could not maintain its proper metabolic function. Methods: The main goal of this paper was to compare qualitatively and semi-quantitatively the amount of both copper and zinc present in the tumor tissue (tissue from patients who had undergone partial or radical nephrectomy) and in the control tissue (which was adjacent to the tumor tissue). This study was carried out using Scanning Electron Microscopy coupled with X-Ray Microanalysis (SEM-XRM). Results: There is a different concentration of copper and zinc in the samples of tumor tissue and controls that were studied. Conclusion: This work complements previously published results about the presence of metals in the human body and their probable influence on carcinogenesis.http://www.ijms.info/ojs/index.php/IJMS/article/view/169CopperZincRenal Cell CarcinomaScanning Electron MicroscopyElectron Probe Microanalysis |
| spellingShingle | Tânia Nogueira Mariana Semedo Elisabete Cunha Essential Heavy Metals in Renal Tumor Tissue and Its Possible Relation to Carcinogenesis: Applying the Scanning Electron Microscopy Coupled with X-Ray Microanalysis Technique International Journal of Medical Students Copper Zinc Renal Cell Carcinoma Scanning Electron Microscopy Electron Probe Microanalysis |
| title | Essential Heavy Metals in Renal Tumor Tissue and Its Possible Relation to Carcinogenesis: Applying the Scanning Electron Microscopy Coupled with X-Ray Microanalysis Technique |
| title_full | Essential Heavy Metals in Renal Tumor Tissue and Its Possible Relation to Carcinogenesis: Applying the Scanning Electron Microscopy Coupled with X-Ray Microanalysis Technique |
| title_fullStr | Essential Heavy Metals in Renal Tumor Tissue and Its Possible Relation to Carcinogenesis: Applying the Scanning Electron Microscopy Coupled with X-Ray Microanalysis Technique |
| title_full_unstemmed | Essential Heavy Metals in Renal Tumor Tissue and Its Possible Relation to Carcinogenesis: Applying the Scanning Electron Microscopy Coupled with X-Ray Microanalysis Technique |
| title_short | Essential Heavy Metals in Renal Tumor Tissue and Its Possible Relation to Carcinogenesis: Applying the Scanning Electron Microscopy Coupled with X-Ray Microanalysis Technique |
| title_sort | essential heavy metals in renal tumor tissue and its possible relation to carcinogenesis applying the scanning electron microscopy coupled with x ray microanalysis technique |
| topic | Copper Zinc Renal Cell Carcinoma Scanning Electron Microscopy Electron Probe Microanalysis |
| url | http://www.ijms.info/ojs/index.php/IJMS/article/view/169 |
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