Concise and Stereospecific Total Synthesis of Arenastatin A and Its Segment B Analogs

Concise and Stereospecific Total Synthesis of Arenastatin A and Its Segment B Analogs

A novel and concise synthetic method for arenastatin A, a cytotoxic cyclic depsipeptide of marine origin, was developed in this study. The convergent assembly of the four segments, including the cross-metathesis reaction, gave a cyclization precursor, and Fmoc deprotection caused simultaneous macroc...

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Detaylı Bibliyografya
Asıl Yazarlar: Yurina Mihara, Haruki Kadoya, Soki Kakihana, Naoyuki Kotoku
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: MDPI AG 2024-08-01
Seri Bilgileri:Molecules
Konular:
arenastatin A
depsipeptide
total synthesis
late-stage diversification
Online Erişim:https://www.mdpi.com/1420-3049/29/17/4058

Internet

https://www.mdpi.com/1420-3049/29/17/4058

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