Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes
Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps o...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-07-01
|
| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00321/full |
| _version_ | 1828156897105018880 |
|---|---|
| author | Kiwamu eHyodo Masanori eKaido Tetsuro eOkuno |
| author_facet | Kiwamu eHyodo Masanori eKaido Tetsuro eOkuno |
| author_sort | Kiwamu eHyodo |
| collection | DOAJ |
| description | Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to several viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes. |
| first_indexed | 2024-04-11T23:20:21Z |
| format | Article |
| id | doaj.art-bfa597784a4b4f49bcc8e4b9a04df8aa |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-04-11T23:20:21Z |
| publishDate | 2014-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-bfa597784a4b4f49bcc8e4b9a04df8aa2022-12-22T03:57:28ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2014-07-01510.3389/fpls.2014.00321100334Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomesKiwamu eHyodo0Masanori eKaido1Tetsuro eOkuno2Kyoto UniversityKyoto UniversityKyoto UniversityMany plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to several viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes.http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00321/fullRNA-Binding Proteincell-to-cell movementRNA replicationRNA virusCellular membrane |
| spellingShingle | Kiwamu eHyodo Masanori eKaido Tetsuro eOkuno Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes Frontiers in Plant Science RNA-Binding Protein cell-to-cell movement RNA replication RNA virus Cellular membrane |
| title | Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes |
| title_full | Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes |
| title_fullStr | Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes |
| title_full_unstemmed | Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes |
| title_short | Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes |
| title_sort | host and viral rna binding proteins involved in membrane targeting replication and intercellular movement of plant rna virus genomes |
| topic | RNA-Binding Protein cell-to-cell movement RNA replication RNA virus Cellular membrane |
| url | http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00321/full |
| work_keys_str_mv | AT kiwamuehyodo hostandviralrnabindingproteinsinvolvedinmembranetargetingreplicationandintercellularmovementofplantrnavirusgenomes AT masanoriekaido hostandviralrnabindingproteinsinvolvedinmembranetargetingreplicationandintercellularmovementofplantrnavirusgenomes AT tetsuroeokuno hostandviralrnabindingproteinsinvolvedinmembranetargetingreplicationandintercellularmovementofplantrnavirusgenomes |