PREDICT FLUID RESPONSIVENESS AFTER OFF-PUMP CORONARY ARTERY BYPASS GRAFTING

Thirty-two adult patients after off-pump coronary artery bypass grafting were enrolled into a prospective observational study. All patients received positive end expiratory pressure test (PEEP-test), mini-fluid challenge test (mFCT) and standard fluid challenge test (sFCT). Pulse pressure variation...

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Main Authors: E. V. Fot, N. N. Isotova, A. A. Smetkin, M. Yu. Kirov
Format: Article
Language:Russian
Published: New Terra Publishing House 2018-11-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/274
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author E. V. Fot
N. N. Isotova
A. A. Smetkin
M. Yu. Kirov
author_facet E. V. Fot
N. N. Isotova
A. A. Smetkin
M. Yu. Kirov
author_sort E. V. Fot
collection DOAJ
description Thirty-two adult patients after off-pump coronary artery bypass grafting were enrolled into a prospective observational study. All patients received positive end expiratory pressure test (PEEP-test), mini-fluid challenge test (mFCT) and standard fluid challenge test (sFCT). Pulse pressure variation using two monitoring systems (PPVPiCCO, PPVNK), Stroke volume variation (SVV), heart-lung index (HLI) and plethysmogram variability index (PVI) were assessed before and after sFCT. The patients with an increase in cardiac index by ≥15% after fluid challenge were defined as fluid responders. According to receiver operating characteristic analysis, changes in mean arterial pressure induced by PEEP-test identified fluid responsiveness with AUC 0.73 (p= 0.03). The reduction in PPVPiCCO and SVV during mFCT predicted positive response to the fluid load with AUC 0.77 and 0.75, respectively (p< 0.05). Response to sFLT can be predicted by the assessment of PPVPiCCO (AUC 0.84), PPVNK (AUC 0.71), SVV (AUC 0.77) and HLI (AUC 0.77) (p< 0.05).
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spelling doaj.art-bfa7729b31fb4716b4013da91ba58e772023-09-03T10:33:16ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532018-11-0115551310.21292/2078-5658-2018-15-5-5-13262PREDICT FLUID RESPONSIVENESS AFTER OFF-PUMP CORONARY ARTERY BYPASS GRAFTINGE. V. Fot0N. N. Isotova1A. A. Smetkin2M. Yu. Kirov3Северный государственный медицинский университет.Северный государственный медицинский университет.Северный государственный медицинский университет.Северный государственный медицинский университет.Thirty-two adult patients after off-pump coronary artery bypass grafting were enrolled into a prospective observational study. All patients received positive end expiratory pressure test (PEEP-test), mini-fluid challenge test (mFCT) and standard fluid challenge test (sFCT). Pulse pressure variation using two monitoring systems (PPVPiCCO, PPVNK), Stroke volume variation (SVV), heart-lung index (HLI) and plethysmogram variability index (PVI) were assessed before and after sFCT. The patients with an increase in cardiac index by ≥15% after fluid challenge were defined as fluid responders. According to receiver operating characteristic analysis, changes in mean arterial pressure induced by PEEP-test identified fluid responsiveness with AUC 0.73 (p= 0.03). The reduction in PPVPiCCO and SVV during mFCT predicted positive response to the fluid load with AUC 0.77 and 0.75, respectively (p< 0.05). Response to sFLT can be predicted by the assessment of PPVPiCCO (AUC 0.84), PPVNK (AUC 0.71), SVV (AUC 0.77) and HLI (AUC 0.77) (p< 0.05).https://www.vair-journal.com/jour/article/view/274восприимчивость к инфузионной нагрузкединамические показателидинамические тесты
spellingShingle E. V. Fot
N. N. Isotova
A. A. Smetkin
M. Yu. Kirov
PREDICT FLUID RESPONSIVENESS AFTER OFF-PUMP CORONARY ARTERY BYPASS GRAFTING
Вестник анестезиологии и реаниматологии
восприимчивость к инфузионной нагрузке
динамические показатели
динамические тесты
title PREDICT FLUID RESPONSIVENESS AFTER OFF-PUMP CORONARY ARTERY BYPASS GRAFTING
title_full PREDICT FLUID RESPONSIVENESS AFTER OFF-PUMP CORONARY ARTERY BYPASS GRAFTING
title_fullStr PREDICT FLUID RESPONSIVENESS AFTER OFF-PUMP CORONARY ARTERY BYPASS GRAFTING
title_full_unstemmed PREDICT FLUID RESPONSIVENESS AFTER OFF-PUMP CORONARY ARTERY BYPASS GRAFTING
title_short PREDICT FLUID RESPONSIVENESS AFTER OFF-PUMP CORONARY ARTERY BYPASS GRAFTING
title_sort predict fluid responsiveness after off pump coronary artery bypass grafting
topic восприимчивость к инфузионной нагрузке
динамические показатели
динамические тесты
url https://www.vair-journal.com/jour/article/view/274
work_keys_str_mv AT evfot predictfluidresponsivenessafteroffpumpcoronaryarterybypassgrafting
AT nnisotova predictfluidresponsivenessafteroffpumpcoronaryarterybypassgrafting
AT aasmetkin predictfluidresponsivenessafteroffpumpcoronaryarterybypassgrafting
AT myukirov predictfluidresponsivenessafteroffpumpcoronaryarterybypassgrafting