MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes

MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes

Abstract Background Diabetes mellitus is characterized by chronic vascular disorder and presents a main risk factor for cardiovascular mortality. In particular, hyperglycaemia and inflammatory cytokines induce vascular circulating tissue factor (TF) that promotes pro-thrombotic conditions in diabete...

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Bibliographic Details
Main Authors: Marco Witkowski, Termeh Tabaraie, Daniel Steffens, Julian Friebel, Andrea Dörner, Carsten Skurk, Mario Witkowski, Bernd Stratmann, Diethelm Tschoepe, Ulf Landmesser, Ursula Rauch
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Cardiovascular Diabetology
Subjects:
Diabetes mellitus
Tissue factor
MicroRNA 19a
Coagulation
Vascular inflammation
Online Access:http://link.springer.com/article/10.1186/s12933-018-0678-z

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