Differential Effects of Alpha 1-Adrenoceptor Antagonists on the Postsynaptic Sensitivity: Using Slice Patch-Clamp Technique for Inhibitory Postsynaptic Current in Substantia Gelatinosa Neurons From Lumbosacral Spinal Cord in Rats

Differential Effects of Alpha 1-Adrenoceptor Antagonists on the Postsynaptic Sensitivity: Using Slice Patch-Clamp Technique for Inhibitory Postsynaptic Current in Substantia Gelatinosa Neurons From Lumbosacral Spinal Cord in Rats

Purpose Alpha1-adrenoceptors participate in improving storage symptoms of male lower urinary tract symptoms. However, the mechanism of action of these compounds remains unclear. The goal of the present study was to clarify the effect of α1- adrenoceptor antagonists on γ-aminobutyric acid (GABA)/glyc...

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Bibliographic Details
Main Authors: Daisuke Uta, Tsuyoshi Hattori, Megumu Yoshimura
Format: Article
Language:English
Published: Korean Continence Society 2020-06-01
Series:International Neurourology Journal
Subjects:
adrenergic alpha-1 receptor antagonists
inhibitory postsynaptic potentials
naftopidil
substantia gelatinosa
Online Access:http://www.einj.org/upload/pdf/inj-1938248-124.pdf

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