Analgesic Effect of Ultrasound-Guided Preoperative Unilateral Lateral Quadratus Lumborum Block for Laparoscopic Nephrectomy: A Randomized, Double-Blinded, Controlled Trial

Kyung-Hwa Kwak,1 Seung Ik Baek,1 Jay Kyoung Kim,1 Tae-Hwan Kim,2 Jinseok Yeo1 1Department of Anesthesiology and Pain Medicine, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, Korea; 2Department of Urology, Kyungpook National University Chilgok...

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Main Authors: Kwak KH, Baek SI, Kim JK, Kim TH, Yeo J
Format: Article
Language:English
Published: Dove Medical Press 2020-07-01
Series:Journal of Pain Research
Subjects:
Online Access:https://www.dovepress.com/analgesic-effect-of-ultrasound-guided-preoperative-unilateral-lateral--peer-reviewed-article-JPR
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author Kwak KH
Baek SI
Kim JK
Kim TH
Yeo J
author_facet Kwak KH
Baek SI
Kim JK
Kim TH
Yeo J
author_sort Kwak KH
collection DOAJ
description Kyung-Hwa Kwak,1 Seung Ik Baek,1 Jay Kyoung Kim,1 Tae-Hwan Kim,2 Jinseok Yeo1 1Department of Anesthesiology and Pain Medicine, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, Korea; 2Department of Urology, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, KoreaCorrespondence: Jinseok YeoDepartment of Anesthesiology and Pain Medicine, Kyungpook National Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, KoreaTel +82 53-200-2644Fax +82 53-200-2027Email painfree@gmail.comPurpose: The quadratus lumborum block (QLB) is a relatively new regional analgesic technique that could provide analgesia to the abdominal wall and reduce postoperative opioid consumption. We investigated the opioid-sparing effect of a unilateral lateral QLB in laparoscopic nephrectomy.Patients and Methods: A total of 60 patients undergoing laparoscopic nephrectomy were included in the study. Patients were randomized into two groups as QLB and control group. QLB group received QLB with 25mL 0.25% ropivacaine, and the control group received 25mL 0.9% saline at anterolateral border of quadratus lumborum muscle preoperatively. Opioid consumption and the pain intensity at rest and on movement were measured at 2nd, 6th, 24th, and 48th hour postoperatively. We also assessed the time to first flatus to measure the extent of paralytic ileus and the quality of recovery-15 (QoR-15) questionnaire.Results: Postoperative opioid consumption was significantly lower in the QLB group than in the control group at 6, 24, and 48h after surgery (P < 0.05). The pain intensity at rest and on movement was significantly lower in the QLB group than in the control group during the first 24 hours after surgery (P < 0.05). The incidence of postoperative nausea and vomiting, time to first flatus, and QoR-15 score did not show significant differences.Conclusion: Preoperative unilateral QLB successfully decreased postoperative pain and opioid consumption after laparoscopic nephrectomy and could be an option for analgesia after laparoscopic nephrectomy.Keywords: quadratus lumborum block, laparoscopic nephrectomy, postoperative pain, opioid consumption, ultrasound-guided block
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spelling doaj.art-bfb03ae019d5446c83f2e98a6b94b10a2022-12-21T22:45:32ZengDove Medical PressJournal of Pain Research1178-70902020-07-01Volume 131647165455048Analgesic Effect of Ultrasound-Guided Preoperative Unilateral Lateral Quadratus Lumborum Block for Laparoscopic Nephrectomy: A Randomized, Double-Blinded, Controlled TrialKwak KHBaek SIKim JKKim THYeo JKyung-Hwa Kwak,1 Seung Ik Baek,1 Jay Kyoung Kim,1 Tae-Hwan Kim,2 Jinseok Yeo1 1Department of Anesthesiology and Pain Medicine, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, Korea; 2Department of Urology, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, KoreaCorrespondence: Jinseok YeoDepartment of Anesthesiology and Pain Medicine, Kyungpook National Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, KoreaTel +82 53-200-2644Fax +82 53-200-2027Email painfree@gmail.comPurpose: The quadratus lumborum block (QLB) is a relatively new regional analgesic technique that could provide analgesia to the abdominal wall and reduce postoperative opioid consumption. We investigated the opioid-sparing effect of a unilateral lateral QLB in laparoscopic nephrectomy.Patients and Methods: A total of 60 patients undergoing laparoscopic nephrectomy were included in the study. Patients were randomized into two groups as QLB and control group. QLB group received QLB with 25mL 0.25% ropivacaine, and the control group received 25mL 0.9% saline at anterolateral border of quadratus lumborum muscle preoperatively. Opioid consumption and the pain intensity at rest and on movement were measured at 2nd, 6th, 24th, and 48th hour postoperatively. We also assessed the time to first flatus to measure the extent of paralytic ileus and the quality of recovery-15 (QoR-15) questionnaire.Results: Postoperative opioid consumption was significantly lower in the QLB group than in the control group at 6, 24, and 48h after surgery (P < 0.05). The pain intensity at rest and on movement was significantly lower in the QLB group than in the control group during the first 24 hours after surgery (P < 0.05). The incidence of postoperative nausea and vomiting, time to first flatus, and QoR-15 score did not show significant differences.Conclusion: Preoperative unilateral QLB successfully decreased postoperative pain and opioid consumption after laparoscopic nephrectomy and could be an option for analgesia after laparoscopic nephrectomy.Keywords: quadratus lumborum block, laparoscopic nephrectomy, postoperative pain, opioid consumption, ultrasound-guided blockhttps://www.dovepress.com/analgesic-effect-of-ultrasound-guided-preoperative-unilateral-lateral--peer-reviewed-article-JPRquadratus lumborum blocklaparoscopic nephrectomypostoperative painopioid consumptionultrasound-guided block
spellingShingle Kwak KH
Baek SI
Kim JK
Kim TH
Yeo J
Analgesic Effect of Ultrasound-Guided Preoperative Unilateral Lateral Quadratus Lumborum Block for Laparoscopic Nephrectomy: A Randomized, Double-Blinded, Controlled Trial
Journal of Pain Research
quadratus lumborum block
laparoscopic nephrectomy
postoperative pain
opioid consumption
ultrasound-guided block
title Analgesic Effect of Ultrasound-Guided Preoperative Unilateral Lateral Quadratus Lumborum Block for Laparoscopic Nephrectomy: A Randomized, Double-Blinded, Controlled Trial
title_full Analgesic Effect of Ultrasound-Guided Preoperative Unilateral Lateral Quadratus Lumborum Block for Laparoscopic Nephrectomy: A Randomized, Double-Blinded, Controlled Trial
title_fullStr Analgesic Effect of Ultrasound-Guided Preoperative Unilateral Lateral Quadratus Lumborum Block for Laparoscopic Nephrectomy: A Randomized, Double-Blinded, Controlled Trial
title_full_unstemmed Analgesic Effect of Ultrasound-Guided Preoperative Unilateral Lateral Quadratus Lumborum Block for Laparoscopic Nephrectomy: A Randomized, Double-Blinded, Controlled Trial
title_short Analgesic Effect of Ultrasound-Guided Preoperative Unilateral Lateral Quadratus Lumborum Block for Laparoscopic Nephrectomy: A Randomized, Double-Blinded, Controlled Trial
title_sort analgesic effect of ultrasound guided preoperative unilateral lateral quadratus lumborum block for laparoscopic nephrectomy a randomized double blinded controlled trial
topic quadratus lumborum block
laparoscopic nephrectomy
postoperative pain
opioid consumption
ultrasound-guided block
url https://www.dovepress.com/analgesic-effect-of-ultrasound-guided-preoperative-unilateral-lateral--peer-reviewed-article-JPR
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