Detoxification of Mycotoxins through Biotransformation
Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions main...
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MDPI AG
2020-02-01
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Series: | Toxins |
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Online Access: | https://www.mdpi.com/2072-6651/12/2/121 |
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author | Peng Li Ruixue Su Ruya Yin Daowan Lai Mingan Wang Yang Liu Ligang Zhou |
author_facet | Peng Li Ruixue Su Ruya Yin Daowan Lai Mingan Wang Yang Liu Ligang Zhou |
author_sort | Peng Li |
collection | DOAJ |
description | Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions mainly include hydroxylation, oxidation, hydrogenation, de-epoxidation, methylation, glycosylation and glucuronidation, esterification, hydrolysis, sulfation, demethylation and deamination. Biotransformations of some notorious mycotoxins such as alfatoxins, alternariol, citrinin, fomannoxin, ochratoxins, patulin, trichothecenes and zearalenone analogues are reviewed in detail. The recent development and applications of mycotoxins detoxification through biotransformation are also discussed. |
first_indexed | 2024-04-14T06:06:00Z |
format | Article |
id | doaj.art-bfbbb53364344c0dbd9f5d31fa78d230 |
institution | Directory Open Access Journal |
issn | 2072-6651 |
language | English |
last_indexed | 2024-04-14T06:06:00Z |
publishDate | 2020-02-01 |
publisher | MDPI AG |
record_format | Article |
series | Toxins |
spelling | doaj.art-bfbbb53364344c0dbd9f5d31fa78d2302022-12-22T02:08:32ZengMDPI AGToxins2072-66512020-02-0112212110.3390/toxins12020121toxins12020121Detoxification of Mycotoxins through BiotransformationPeng Li0Ruixue Su1Ruya Yin2Daowan Lai3Mingan Wang4Yang Liu5Ligang Zhou6Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaDepartment of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaDepartment of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaDepartment of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaDepartment of Applied Chemistry, College of Sciences, China Agricultural University, Beijing 100193, ChinaInstitute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, ChinaDepartment of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaMycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions mainly include hydroxylation, oxidation, hydrogenation, de-epoxidation, methylation, glycosylation and glucuronidation, esterification, hydrolysis, sulfation, demethylation and deamination. Biotransformations of some notorious mycotoxins such as alfatoxins, alternariol, citrinin, fomannoxin, ochratoxins, patulin, trichothecenes and zearalenone analogues are reviewed in detail. The recent development and applications of mycotoxins detoxification through biotransformation are also discussed.https://www.mdpi.com/2072-6651/12/2/121fungimycotoxinsphytotoxinsdetoxificationbiotransformationliving organismsenzymesfood safety and feed safety |
spellingShingle | Peng Li Ruixue Su Ruya Yin Daowan Lai Mingan Wang Yang Liu Ligang Zhou Detoxification of Mycotoxins through Biotransformation Toxins fungi mycotoxins phytotoxins detoxification biotransformation living organisms enzymes food safety and feed safety |
title | Detoxification of Mycotoxins through Biotransformation |
title_full | Detoxification of Mycotoxins through Biotransformation |
title_fullStr | Detoxification of Mycotoxins through Biotransformation |
title_full_unstemmed | Detoxification of Mycotoxins through Biotransformation |
title_short | Detoxification of Mycotoxins through Biotransformation |
title_sort | detoxification of mycotoxins through biotransformation |
topic | fungi mycotoxins phytotoxins detoxification biotransformation living organisms enzymes food safety and feed safety |
url | https://www.mdpi.com/2072-6651/12/2/121 |
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