Detoxification of Mycotoxins through Biotransformation

Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions main...

Full description

Bibliographic Details
Main Authors: Peng Li, Ruixue Su, Ruya Yin, Daowan Lai, Mingan Wang, Yang Liu, Ligang Zhou
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/2/121
_version_ 1818011294789271552
author Peng Li
Ruixue Su
Ruya Yin
Daowan Lai
Mingan Wang
Yang Liu
Ligang Zhou
author_facet Peng Li
Ruixue Su
Ruya Yin
Daowan Lai
Mingan Wang
Yang Liu
Ligang Zhou
author_sort Peng Li
collection DOAJ
description Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions mainly include hydroxylation, oxidation, hydrogenation, de-epoxidation, methylation, glycosylation and glucuronidation, esterification, hydrolysis, sulfation, demethylation and deamination. Biotransformations of some notorious mycotoxins such as alfatoxins, alternariol, citrinin, fomannoxin, ochratoxins, patulin, trichothecenes and zearalenone analogues are reviewed in detail. The recent development and applications of mycotoxins detoxification through biotransformation are also discussed.
first_indexed 2024-04-14T06:06:00Z
format Article
id doaj.art-bfbbb53364344c0dbd9f5d31fa78d230
institution Directory Open Access Journal
issn 2072-6651
language English
last_indexed 2024-04-14T06:06:00Z
publishDate 2020-02-01
publisher MDPI AG
record_format Article
series Toxins
spelling doaj.art-bfbbb53364344c0dbd9f5d31fa78d2302022-12-22T02:08:32ZengMDPI AGToxins2072-66512020-02-0112212110.3390/toxins12020121toxins12020121Detoxification of Mycotoxins through BiotransformationPeng Li0Ruixue Su1Ruya Yin2Daowan Lai3Mingan Wang4Yang Liu5Ligang Zhou6Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaDepartment of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaDepartment of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaDepartment of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaDepartment of Applied Chemistry, College of Sciences, China Agricultural University, Beijing 100193, ChinaInstitute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, ChinaDepartment of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, ChinaMycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions mainly include hydroxylation, oxidation, hydrogenation, de-epoxidation, methylation, glycosylation and glucuronidation, esterification, hydrolysis, sulfation, demethylation and deamination. Biotransformations of some notorious mycotoxins such as alfatoxins, alternariol, citrinin, fomannoxin, ochratoxins, patulin, trichothecenes and zearalenone analogues are reviewed in detail. The recent development and applications of mycotoxins detoxification through biotransformation are also discussed.https://www.mdpi.com/2072-6651/12/2/121fungimycotoxinsphytotoxinsdetoxificationbiotransformationliving organismsenzymesfood safety and feed safety
spellingShingle Peng Li
Ruixue Su
Ruya Yin
Daowan Lai
Mingan Wang
Yang Liu
Ligang Zhou
Detoxification of Mycotoxins through Biotransformation
Toxins
fungi
mycotoxins
phytotoxins
detoxification
biotransformation
living organisms
enzymes
food safety and feed safety
title Detoxification of Mycotoxins through Biotransformation
title_full Detoxification of Mycotoxins through Biotransformation
title_fullStr Detoxification of Mycotoxins through Biotransformation
title_full_unstemmed Detoxification of Mycotoxins through Biotransformation
title_short Detoxification of Mycotoxins through Biotransformation
title_sort detoxification of mycotoxins through biotransformation
topic fungi
mycotoxins
phytotoxins
detoxification
biotransformation
living organisms
enzymes
food safety and feed safety
url https://www.mdpi.com/2072-6651/12/2/121
work_keys_str_mv AT pengli detoxificationofmycotoxinsthroughbiotransformation
AT ruixuesu detoxificationofmycotoxinsthroughbiotransformation
AT ruyayin detoxificationofmycotoxinsthroughbiotransformation
AT daowanlai detoxificationofmycotoxinsthroughbiotransformation
AT minganwang detoxificationofmycotoxinsthroughbiotransformation
AT yangliu detoxificationofmycotoxinsthroughbiotransformation
AT ligangzhou detoxificationofmycotoxinsthroughbiotransformation