A Nickel-Containing Polyoxomolybdate as an Efficient Antibacterial Agent for Water Treatment
In view of the water pollution issues caused by pathogenic microorganisms and harmful organic contaminants, nontoxic, environmentally friendly, and efficient antimicrobial agents are urgently required. Herein, a nickel-based Keggin polyoxomolybdate [Ni(L)(HL)]<sub>2</sub>H[PMo<sub>...
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MDPI AG
2022-08-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/17/9651 |
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| author | Jiangnan Chang Mingxue Li Jiyuan Du Min Ma Cuili Xing Lin Sun Pengtao Ma |
| author_facet | Jiangnan Chang Mingxue Li Jiyuan Du Min Ma Cuili Xing Lin Sun Pengtao Ma |
| author_sort | Jiangnan Chang |
| collection | DOAJ |
| description | In view of the water pollution issues caused by pathogenic microorganisms and harmful organic contaminants, nontoxic, environmentally friendly, and efficient antimicrobial agents are urgently required. Herein, a nickel-based Keggin polyoxomolybdate [Ni(L)(HL)]<sub>2</sub>H[PMo<sub>12</sub>O<sub>40</sub>] 4H<sub>2</sub>O (<b>1</b>, HL = 2-acetylpyrazine thiosemicarbazone) was prepared via a facile hydrothermal method and successfully characterized. Compound <b>1</b> exhibited high stability in a wide range of pH values from 4 to 10. <b>1</b> demonstrated significant antibacterial activity, with minimum inhibitory concentration (MIC) values in the range of 0.0019–0.2400 µg/mL against four types of bacteria, including <i>Staphylococcus aureus</i> (<i>S. aureus</i>), <i>Bacillus subtilis</i> (<i>B. subtilis</i>), <i>Escherichia coli</i> (<i>E. coli</i>), and <i>Agrobacterium tumefaciens</i> (<i>A. tumefaciens</i>). Further time-kill studies indicated that <b>1</b> killed almost all (99.9%) of <i>E. coli</i> and <i>S. aureus.</i> Meanwhile, the possible antibacterial mechanism was explored, and the results indicate that the antibacterial properties of <b>1</b> originate from the synergistic effect between [Ni(L)(HL)]<sup>+</sup> and [PMo<sub>12</sub>O<sub>40</sub>]<sup>3−</sup>. In addition, <b>1</b> presented effective adsorption of basic fuchsin (BF) dyes. The kinetic data fitted a pseudo-second-order kinetic model well, and the maximum adsorption efficiency for the BF dyes (29.81 mg/g) was determined by the data fit of the Freundlich isotherm model. The results show that BF adsorption was dominated by both chemical adsorption and multilayer adsorption. This work provides evidence that <b>1</b> has potential to effectively remove dyes and pathogenic bacteria from wastewater. |
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| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T01:46:30Z |
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| spelling | doaj.art-bfbea4bd225a43689add2f78ff0b6dca2023-11-23T13:14:25ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-08-012317965110.3390/ijms23179651A Nickel-Containing Polyoxomolybdate as an Efficient Antibacterial Agent for Water TreatmentJiangnan Chang0Mingxue Li1Jiyuan Du2Min Ma3Cuili Xing4Lin Sun5Pengtao Ma6Henan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, ChinaHenan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, ChinaHenan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, ChinaHenan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, ChinaHenan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, ChinaHenan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, ChinaHenan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, ChinaIn view of the water pollution issues caused by pathogenic microorganisms and harmful organic contaminants, nontoxic, environmentally friendly, and efficient antimicrobial agents are urgently required. Herein, a nickel-based Keggin polyoxomolybdate [Ni(L)(HL)]<sub>2</sub>H[PMo<sub>12</sub>O<sub>40</sub>] 4H<sub>2</sub>O (<b>1</b>, HL = 2-acetylpyrazine thiosemicarbazone) was prepared via a facile hydrothermal method and successfully characterized. Compound <b>1</b> exhibited high stability in a wide range of pH values from 4 to 10. <b>1</b> demonstrated significant antibacterial activity, with minimum inhibitory concentration (MIC) values in the range of 0.0019–0.2400 µg/mL against four types of bacteria, including <i>Staphylococcus aureus</i> (<i>S. aureus</i>), <i>Bacillus subtilis</i> (<i>B. subtilis</i>), <i>Escherichia coli</i> (<i>E. coli</i>), and <i>Agrobacterium tumefaciens</i> (<i>A. tumefaciens</i>). Further time-kill studies indicated that <b>1</b> killed almost all (99.9%) of <i>E. coli</i> and <i>S. aureus.</i> Meanwhile, the possible antibacterial mechanism was explored, and the results indicate that the antibacterial properties of <b>1</b> originate from the synergistic effect between [Ni(L)(HL)]<sup>+</sup> and [PMo<sub>12</sub>O<sub>40</sub>]<sup>3−</sup>. In addition, <b>1</b> presented effective adsorption of basic fuchsin (BF) dyes. The kinetic data fitted a pseudo-second-order kinetic model well, and the maximum adsorption efficiency for the BF dyes (29.81 mg/g) was determined by the data fit of the Freundlich isotherm model. The results show that BF adsorption was dominated by both chemical adsorption and multilayer adsorption. This work provides evidence that <b>1</b> has potential to effectively remove dyes and pathogenic bacteria from wastewater.https://www.mdpi.com/1422-0067/23/17/9651polyoxomolybdateantibacterial activityantibacterial mechanismadsorption properties |
| spellingShingle | Jiangnan Chang Mingxue Li Jiyuan Du Min Ma Cuili Xing Lin Sun Pengtao Ma A Nickel-Containing Polyoxomolybdate as an Efficient Antibacterial Agent for Water Treatment International Journal of Molecular Sciences polyoxomolybdate antibacterial activity antibacterial mechanism adsorption properties |
| title | A Nickel-Containing Polyoxomolybdate as an Efficient Antibacterial Agent for Water Treatment |
| title_full | A Nickel-Containing Polyoxomolybdate as an Efficient Antibacterial Agent for Water Treatment |
| title_fullStr | A Nickel-Containing Polyoxomolybdate as an Efficient Antibacterial Agent for Water Treatment |
| title_full_unstemmed | A Nickel-Containing Polyoxomolybdate as an Efficient Antibacterial Agent for Water Treatment |
| title_short | A Nickel-Containing Polyoxomolybdate as an Efficient Antibacterial Agent for Water Treatment |
| title_sort | nickel containing polyoxomolybdate as an efficient antibacterial agent for water treatment |
| topic | polyoxomolybdate antibacterial activity antibacterial mechanism adsorption properties |
| url | https://www.mdpi.com/1422-0067/23/17/9651 |
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