Evaluations of bacterial contaminated full thickness burn wound healing in Sprague Dawley rats Treated with Tualang honey
Aim: The effect of Tualang honey on wound healing in bacterial contaminated full-thickness burn wounds was evaluated in 36 male Sprague Dawley rats. Materials and Methods: The rats were randomly divided into three groups (n = 12/group). Three full-thickness burn wounds were created on each rat. Each...
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2011-01-01
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| Series: | Indian Journal of Plastic Surgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699489 |
| _version_ | 1818286014503845888 |
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| author | Salmi Mohamed Sukur Ahmad Sukari Halim Kirnpal Kaur Banga Singh |
| author_facet | Salmi Mohamed Sukur Ahmad Sukari Halim Kirnpal Kaur Banga Singh |
| author_sort | Salmi Mohamed Sukur |
| collection | DOAJ |
| description | Aim: The effect of Tualang honey on wound healing in bacterial contaminated full-thickness burn wounds was evaluated in 36 male Sprague Dawley rats. Materials and Methods: The rats were randomly divided into three groups (n = 12/group). Three full-thickness burn wounds were created on each rat. Each group of rats was inoculated with a different organism in the burn wounds: Group A was inoculated with Pseudomonas aeruginosa, Group B was inoculated with Klebsiella pneumoniae and Group C was inoculated with Acinetobacter baumannii. One wound on each rat was dressed with either Tualang honey, Chitosan gel or Hydrofibre silver. Each wound size was measured on day 3, 6, 9, 12, 15, 18 and 21 of the study. Results: The mean wound size of the Tualang honey-treated wounds was not statistically different than that of the Chitosan gel or Hydrofibre silver-treated wounds when the wounds were compared throughout the entire experiment (P > 0.05). However, comparing the mean wound size on day 21 alone revealed that the Tualang honey-treated wounds were smaller in comparison to that of the Chitosan gel and Hydrofibre silver-treated groups. Conclusions: This study shows that topical application of Tualang honey on burn wounds contaminated with P. aeruginosa and A. baumannii gave the fastest rate of healing compared with other treatments. |
| first_indexed | 2024-12-13T01:17:51Z |
| format | Article |
| id | doaj.art-bfc02e4e23a945088f86a479c66c7ae2 |
| institution | Directory Open Access Journal |
| issn | 0970-0358 1998-376X |
| language | English |
| last_indexed | 2024-12-13T01:17:51Z |
| publishDate | 2011-01-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Indian Journal of Plastic Surgery |
| spelling | doaj.art-bfc02e4e23a945088f86a479c66c7ae22022-12-22T00:04:18ZengThieme Medical Publishers, Inc.Indian Journal of Plastic Surgery0970-03581998-376X2011-01-01440111211710.1055/s-0039-1699489Evaluations of bacterial contaminated full thickness burn wound healing in Sprague Dawley rats Treated with Tualang honeySalmi Mohamed Sukur0Ahmad Sukari Halim1Kirnpal Kaur Banga Singh2Reconstructive Sciences Unit, Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains MalaysiaReconstructive Sciences Unit, Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains MalaysiaReconstructive Sciences Unit, Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains MalaysiaAim: The effect of Tualang honey on wound healing in bacterial contaminated full-thickness burn wounds was evaluated in 36 male Sprague Dawley rats. Materials and Methods: The rats were randomly divided into three groups (n = 12/group). Three full-thickness burn wounds were created on each rat. Each group of rats was inoculated with a different organism in the burn wounds: Group A was inoculated with Pseudomonas aeruginosa, Group B was inoculated with Klebsiella pneumoniae and Group C was inoculated with Acinetobacter baumannii. One wound on each rat was dressed with either Tualang honey, Chitosan gel or Hydrofibre silver. Each wound size was measured on day 3, 6, 9, 12, 15, 18 and 21 of the study. Results: The mean wound size of the Tualang honey-treated wounds was not statistically different than that of the Chitosan gel or Hydrofibre silver-treated wounds when the wounds were compared throughout the entire experiment (P > 0.05). However, comparing the mean wound size on day 21 alone revealed that the Tualang honey-treated wounds were smaller in comparison to that of the Chitosan gel and Hydrofibre silver-treated groups. Conclusions: This study shows that topical application of Tualang honey on burn wounds contaminated with P. aeruginosa and A. baumannii gave the fastest rate of healing compared with other treatments.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699489burn woundhoney pseudomonas aeruginosa acinetobacter baumannii, wound healing |
| spellingShingle | Salmi Mohamed Sukur Ahmad Sukari Halim Kirnpal Kaur Banga Singh Evaluations of bacterial contaminated full thickness burn wound healing in Sprague Dawley rats Treated with Tualang honey Indian Journal of Plastic Surgery burn wound honey pseudomonas aeruginosa acinetobacter baumannii, wound healing |
| title | Evaluations of bacterial contaminated full thickness burn wound healing in Sprague Dawley rats Treated with Tualang honey |
| title_full | Evaluations of bacterial contaminated full thickness burn wound healing in Sprague Dawley rats Treated with Tualang honey |
| title_fullStr | Evaluations of bacterial contaminated full thickness burn wound healing in Sprague Dawley rats Treated with Tualang honey |
| title_full_unstemmed | Evaluations of bacterial contaminated full thickness burn wound healing in Sprague Dawley rats Treated with Tualang honey |
| title_short | Evaluations of bacterial contaminated full thickness burn wound healing in Sprague Dawley rats Treated with Tualang honey |
| title_sort | evaluations of bacterial contaminated full thickness burn wound healing in sprague dawley rats treated with tualang honey |
| topic | burn wound honey pseudomonas aeruginosa acinetobacter baumannii, wound healing |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1699489 |
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