Prioritizing post-COVID-19 health research in sub-Saharan Africa: A modified Delphi study for future pandemic

Background: The COVID-19 pandemic exposed weaknesses in healthcare systems and disparities in healthcare access across sub-Saharan Africa (SSA). The insights of frontline healthcare professionals (HCPs), and healthcare researchers involved with the response to COVID in SSA are crucial to ensuring th...

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Main Authors: Emilia Virginia Noormahomed, Michael J A Reid, Aloysius Gonzaga Mubuuke, Onesmus Gachuno, Nelson K. Sewankambo, Aster Tsegaye, Jess Celentano, Elsie Kiguli-Malwadde, Mamudo Ismail, Georgina Odaibo, Nthabiseng Phaladze, Jean B. Nachega
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Scientific African
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468227624000486
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author Emilia Virginia Noormahomed
Michael J A Reid
Aloysius Gonzaga Mubuuke
Onesmus Gachuno
Nelson K. Sewankambo
Aster Tsegaye
Jess Celentano
Elsie Kiguli-Malwadde
Mamudo Ismail
Georgina Odaibo
Nthabiseng Phaladze
Jean B. Nachega
author_facet Emilia Virginia Noormahomed
Michael J A Reid
Aloysius Gonzaga Mubuuke
Onesmus Gachuno
Nelson K. Sewankambo
Aster Tsegaye
Jess Celentano
Elsie Kiguli-Malwadde
Mamudo Ismail
Georgina Odaibo
Nthabiseng Phaladze
Jean B. Nachega
author_sort Emilia Virginia Noormahomed
collection DOAJ
description Background: The COVID-19 pandemic exposed weaknesses in healthcare systems and disparities in healthcare access across sub-Saharan Africa (SSA). The insights of frontline healthcare professionals (HCPs), and healthcare researchers involved with the response to COVID in SSA are crucial to ensuring that health systems are optimally prepared for the next pandemic threat. Nonetheless, there is limited consensus as to what are the clinical and public health research priorities necessary to ensure that SSA is optimally prepared and responsive to future pandemics. The aim of this Delphi consensus process was to collate the insights of leading HCPs engaged in research and clinical practice across SSA and prioritize a set of post-COVID-19 pandemic research priorities and determine the investment agenda necessary to address those priorities Methods: A modified Delphi process was designed to prioritize a shared agenda. A group of researchers from the African Forum for Research and Education in Health (AFREhealth) were asked to first list potential research topics. Then, members of the broader AFREhealth community were invited to rate the importance of each topic on a 4-point Likert scale, through two rounds of consensus-seeking. Consensus for inclusion was predefined as ≥70 % of respondents' rating. Results: Health professionals, academics, and scientists representing a variety of professions from twenty SSA countries responded to the survey rounds, delivered electronically. An initial subset of researchers suggested 11 initial topics; subsequently, 53 respondents completed round one, and 64 completed round two of the modified Delphi. A final list of 20 topics that met predetermined consensus was grouped into four technical domains: [1] Health workforce and health professions education research; [2] Epidemiology and surveillance; [3] Clinical and health systems research; and [4] and other cross-cutting topics. Across these four domains, the highest-ranking priorities included [1] leveraging digital tools to enhance the health workforce, [2] strengthening genomic surveillance, [3] assessing health system resiliency, and [4] conducting ethical research. Conclusions: Post-pandemic research priorities for pandemic preparedness and response included strategies to determine to leverage digital tools to enhance workforce training and impact, leveraging genomic surveillance capacity to close epidemiologic gaps, and developing strategies to enhance health system resiliency. The priorities outlined in this analysis underscore the need for capacity-building and context-specific research in sub-Saharan Africa to ensure an effective and equitable response to future pandemics.
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spelling doaj.art-bfc5b2c8df874289a7f0bf49c7a9c9b02024-03-05T04:30:37ZengElsevierScientific African2468-22762024-03-0123e02103Prioritizing post-COVID-19 health research in sub-Saharan Africa: A modified Delphi study for future pandemicEmilia Virginia Noormahomed0Michael J A Reid1Aloysius Gonzaga Mubuuke2Onesmus Gachuno3Nelson K. Sewankambo4Aster Tsegaye5Jess Celentano6Elsie Kiguli-Malwadde7Mamudo Ismail8Georgina Odaibo9Nthabiseng Phaladze10Jean B. Nachega11Universidade Eduardo Mondlane, Maputo, MozambiqueUniversity of California, San Francisco, CA, USA; Corresponding author at: Institute for Global Health Sciences, UCSF 550 16th Street, 3rd Floor, San Francisco, California 94158.Makerere University, Kampala, UgandaUniversity of Nairobi, Nairobi, KenyaMakerere University, Kampala, UgandaAddis Ababa University, College of Health Sciences, Addis Ababa, EthiopiaUniversity of California, San Francisco, CA, USAAfrican Centre for Global Health & Social Transformation (ACHEST), Kampala, UgandaUniversidade Eduardo Mondlane, Maputo, MozambiqueUniversity of Ibadan, Ibadan, NigeriaUniversity of Botswana, Faculty of Health Sciences, Gaborone, BotswanaUniversity of Pittsburgh, Pittsburgh, PA, USA; Stellenbosch University, Cape Town, South Africa; Johns Hopkins University, Baltimore, MD, USABackground: The COVID-19 pandemic exposed weaknesses in healthcare systems and disparities in healthcare access across sub-Saharan Africa (SSA). The insights of frontline healthcare professionals (HCPs), and healthcare researchers involved with the response to COVID in SSA are crucial to ensuring that health systems are optimally prepared for the next pandemic threat. Nonetheless, there is limited consensus as to what are the clinical and public health research priorities necessary to ensure that SSA is optimally prepared and responsive to future pandemics. The aim of this Delphi consensus process was to collate the insights of leading HCPs engaged in research and clinical practice across SSA and prioritize a set of post-COVID-19 pandemic research priorities and determine the investment agenda necessary to address those priorities Methods: A modified Delphi process was designed to prioritize a shared agenda. A group of researchers from the African Forum for Research and Education in Health (AFREhealth) were asked to first list potential research topics. Then, members of the broader AFREhealth community were invited to rate the importance of each topic on a 4-point Likert scale, through two rounds of consensus-seeking. Consensus for inclusion was predefined as ≥70 % of respondents' rating. Results: Health professionals, academics, and scientists representing a variety of professions from twenty SSA countries responded to the survey rounds, delivered electronically. An initial subset of researchers suggested 11 initial topics; subsequently, 53 respondents completed round one, and 64 completed round two of the modified Delphi. A final list of 20 topics that met predetermined consensus was grouped into four technical domains: [1] Health workforce and health professions education research; [2] Epidemiology and surveillance; [3] Clinical and health systems research; and [4] and other cross-cutting topics. Across these four domains, the highest-ranking priorities included [1] leveraging digital tools to enhance the health workforce, [2] strengthening genomic surveillance, [3] assessing health system resiliency, and [4] conducting ethical research. Conclusions: Post-pandemic research priorities for pandemic preparedness and response included strategies to determine to leverage digital tools to enhance workforce training and impact, leveraging genomic surveillance capacity to close epidemiologic gaps, and developing strategies to enhance health system resiliency. The priorities outlined in this analysis underscore the need for capacity-building and context-specific research in sub-Saharan Africa to ensure an effective and equitable response to future pandemics.http://www.sciencedirect.com/science/article/pii/S2468227624000486Delphi methodologyPandemic preparednessSub-Saharan Africa healthcarePost-COVID-19 challengesHealth professions trainingResearch institutions in Africa
spellingShingle Emilia Virginia Noormahomed
Michael J A Reid
Aloysius Gonzaga Mubuuke
Onesmus Gachuno
Nelson K. Sewankambo
Aster Tsegaye
Jess Celentano
Elsie Kiguli-Malwadde
Mamudo Ismail
Georgina Odaibo
Nthabiseng Phaladze
Jean B. Nachega
Prioritizing post-COVID-19 health research in sub-Saharan Africa: A modified Delphi study for future pandemic
Scientific African
Delphi methodology
Pandemic preparedness
Sub-Saharan Africa healthcare
Post-COVID-19 challenges
Health professions training
Research institutions in Africa
title Prioritizing post-COVID-19 health research in sub-Saharan Africa: A modified Delphi study for future pandemic
title_full Prioritizing post-COVID-19 health research in sub-Saharan Africa: A modified Delphi study for future pandemic
title_fullStr Prioritizing post-COVID-19 health research in sub-Saharan Africa: A modified Delphi study for future pandemic
title_full_unstemmed Prioritizing post-COVID-19 health research in sub-Saharan Africa: A modified Delphi study for future pandemic
title_short Prioritizing post-COVID-19 health research in sub-Saharan Africa: A modified Delphi study for future pandemic
title_sort prioritizing post covid 19 health research in sub saharan africa a modified delphi study for future pandemic
topic Delphi methodology
Pandemic preparedness
Sub-Saharan Africa healthcare
Post-COVID-19 challenges
Health professions training
Research institutions in Africa
url http://www.sciencedirect.com/science/article/pii/S2468227624000486
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