Alpha2-Adrenergic Receptors as a Pharmacological Target for Spike-Wave Epilepsy
Spike-wave discharges are the hallmark of idiopathic generalized epilepsy. They are caused by a disorder in the thalamocortical network. Commercially available anti-epileptic drugs have pronounced side effects (i.e., sedation and gastroenterological concerns), which might result from a low selectivi...
Main Authors: | Evgenia Sitnikova, Elizaveta Rutskova, Kirill Smirnov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/2/1477 |
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