2-hydroxylated sphingomyelin profiles in cells from patients with mutated fatty acid 2-hydroxylase

2-hydroxylated sphingomyelin profiles in cells from patients with mutated fatty acid 2-hydroxylase

<p>Abstract</p> <p>Fatty acid 2-hydroxylase (FA2H) is the enzyme responsible for the hydroxylation of free fatty acids prior to their incorporation into 2-hydroxylated sphingolipids, which are the major constituents of the myelin leaflet. Mutated FA2H has been associated with neuro...

Full description

Bibliographic Details
Main Authors: Saada Ann, Hama Hiroko, Bielawski Jacek, Edvardson Simon, Dan Phyllis
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Lipids in Health and Disease
Subjects:
Fatty acid hydroxylase
hydroxylated fatty acid sphingomyelin
autosomal recessive leukodystrophy
Online Access:http://www.lipidworld.com/content/10/1/84

Similar Items

Similar Items