Rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of Sjögren's syndrome: a case report
<p>Abstract</p> <p>Introduction</p> <p>Rectal mucosal prolapse syndrome, histologically characterized by fibromuscular obliteration in the lamina propria, hyperplastic glands and thickened muscularis mucosa, causes rectal bleeding. Sjögren's syndrome is an autoimmu...
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BMC
2009-10-01
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Series: | Journal of Medical Case Reports |
Online Access: | http://www.jmedicalcasereports.com/content/3/1/85 |
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author | Koga Hideki Shimizu Kayoko Tarumi Ken-ichi Sadahira Yoshito Matsumoto Takayuki Iida Mitsuo Haruma Ken |
author_facet | Koga Hideki Shimizu Kayoko Tarumi Ken-ichi Sadahira Yoshito Matsumoto Takayuki Iida Mitsuo Haruma Ken |
author_sort | Koga Hideki |
collection | DOAJ |
description | <p>Abstract</p> <p>Introduction</p> <p>Rectal mucosal prolapse syndrome, histologically characterized by fibromuscular obliteration in the lamina propria, hyperplastic glands and thickened muscularis mucosa, causes rectal bleeding. Sjögren's syndrome is an autoimmune exocrinopathy that chiefly destroys the salivary and lacrimal glands by lympho-plasmacytic infiltration. Although various gastrointestinal manifestations have been reported in patients with Sjögren's syndrome, there have not been to our knowledge any case reports to date of rectal mucosal prolapse syndrome in association with Sjögren's syndrome.</p> <p>Case presentation</p> <p>A 68-year-old Japanese woman with Sjögren's syndrome and long-term constipation consulted our hospital because of rectal bleeding. Because of dysphagia and xerostomia, she had consistently refused recommendations to take oral medicines including cathartics. Therefore, she frequently strained excessively during defecation. Colonoscopy and radiological examinations disclosed eroded flat protrusions of the rectum. Microscopic examination demonstrated inflamed mucosa with elongated tortuous glands and fibromuscular obliteration. Based on these findings, a diagnosis of rectal mucosal prolapse syndrome was made. Prohibition of straining during defecation and sulfasalazine suppository use were effective.</p> <p>Conclusion</p> <p>This case highlights the importance of defecation control in patients with Sjögren's syndrome. In the case presented, rectal mucosal prolapse syndrome following long-term excessive straining during defecation caused rectal bleeding. Clinicians should consider rectal mucosal prolapse syndrome as a gastrointestinal manifestation of Sjögren's syndrome.</p> |
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issn | 1752-1947 |
language | English |
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series | Journal of Medical Case Reports |
spelling | doaj.art-bfc96647cb5e4bda8119ffa57283e33a2022-12-22T01:10:52ZengBMCJournal of Medical Case Reports1752-19472009-10-01318510.1186/1752-1947-3-85Rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of Sjögren's syndrome: a case reportKoga HidekiShimizu KayokoTarumi Ken-ichiSadahira YoshitoMatsumoto TakayukiIida MitsuoHaruma Ken<p>Abstract</p> <p>Introduction</p> <p>Rectal mucosal prolapse syndrome, histologically characterized by fibromuscular obliteration in the lamina propria, hyperplastic glands and thickened muscularis mucosa, causes rectal bleeding. Sjögren's syndrome is an autoimmune exocrinopathy that chiefly destroys the salivary and lacrimal glands by lympho-plasmacytic infiltration. Although various gastrointestinal manifestations have been reported in patients with Sjögren's syndrome, there have not been to our knowledge any case reports to date of rectal mucosal prolapse syndrome in association with Sjögren's syndrome.</p> <p>Case presentation</p> <p>A 68-year-old Japanese woman with Sjögren's syndrome and long-term constipation consulted our hospital because of rectal bleeding. Because of dysphagia and xerostomia, she had consistently refused recommendations to take oral medicines including cathartics. Therefore, she frequently strained excessively during defecation. Colonoscopy and radiological examinations disclosed eroded flat protrusions of the rectum. Microscopic examination demonstrated inflamed mucosa with elongated tortuous glands and fibromuscular obliteration. Based on these findings, a diagnosis of rectal mucosal prolapse syndrome was made. Prohibition of straining during defecation and sulfasalazine suppository use were effective.</p> <p>Conclusion</p> <p>This case highlights the importance of defecation control in patients with Sjögren's syndrome. In the case presented, rectal mucosal prolapse syndrome following long-term excessive straining during defecation caused rectal bleeding. Clinicians should consider rectal mucosal prolapse syndrome as a gastrointestinal manifestation of Sjögren's syndrome.</p>http://www.jmedicalcasereports.com/content/3/1/85 |
spellingShingle | Koga Hideki Shimizu Kayoko Tarumi Ken-ichi Sadahira Yoshito Matsumoto Takayuki Iida Mitsuo Haruma Ken Rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of Sjögren's syndrome: a case report Journal of Medical Case Reports |
title | Rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of Sjögren's syndrome: a case report |
title_full | Rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of Sjögren's syndrome: a case report |
title_fullStr | Rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of Sjögren's syndrome: a case report |
title_full_unstemmed | Rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of Sjögren's syndrome: a case report |
title_short | Rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of Sjögren's syndrome: a case report |
title_sort | rectal mucosal prolapse syndrome as an unusual gastrointestinal manifestation of sjogren s syndrome a case report |
url | http://www.jmedicalcasereports.com/content/3/1/85 |
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