Efficacy on gait and posture control after botulinum toxin A injection for lower-limb spasticity treatment after stroke: A randomized controlled trial
ObjectivesTo observe the efficacy of botulinum toxin type A (BoNT-A) for the spasticity of the lower-limb post-stroke on gait and posture control.MethodsA total of 46 patients with hemiplegia gait were randomly divided into the experimental group (23 patients) and the control group (23 patients). In...
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2022.1107688/full |
| _version_ | 1797952098949660672 |
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| author | Hui-xian Yu Si-hao Liu Zhao-xia Wang Chang-bin Liu Pei Dai Da-wei Zang |
| author_facet | Hui-xian Yu Si-hao Liu Zhao-xia Wang Chang-bin Liu Pei Dai Da-wei Zang |
| author_sort | Hui-xian Yu |
| collection | DOAJ |
| description | ObjectivesTo observe the efficacy of botulinum toxin type A (BoNT-A) for the spasticity of the lower-limb post-stroke on gait and posture control.MethodsA total of 46 patients with hemiplegia gait were randomly divided into the experimental group (23 patients) and the control group (23 patients). In patients in the experimental group received injections of BoNT-A by electrical stimulation-guided. At the same time, patients of the two groups received routine physical therapy. Gait analysis, plantar pressure analysis, lower-limb Fugl–Meyer assessment (L-FMA), 10 meter walking test (10MWT), timed “Up and Go” test (TUGT), and modified Ashworth Scale assess (MAS) of the lower limbs were performed at 0, 1, 4, and 12 weeks after treatment.ResultsAt 1, 4, and 12 weeks after treatment, the L-FMA, stride length, speed, and TUGT significantly improved than 0 week in both groups. The L-FMA and peak of forefoot pressure, and MAS results in the experimental group were better than those in the control group at 4 and 12 weeks. The TUGT, speed, and stride length in experimental group was significantly shortened than that in control group at 1, 4, and 12 weeks.ConclusionBotulinum toxin type A injection can improve motor functions of the lower limb, gait, spasticity, forefoot pressure, and posture control of patients after stroke. |
| first_indexed | 2024-04-10T22:42:06Z |
| format | Article |
| id | doaj.art-bfc9b380aae340f383f200ffff981ed8 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-04-10T22:42:06Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Neuroscience |
| spelling | doaj.art-bfc9b380aae340f383f200ffff981ed82023-01-16T04:52:48ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2023-01-011610.3389/fnins.2022.11076881107688Efficacy on gait and posture control after botulinum toxin A injection for lower-limb spasticity treatment after stroke: A randomized controlled trialHui-xian YuSi-hao LiuZhao-xia WangChang-bin LiuPei DaiDa-wei ZangObjectivesTo observe the efficacy of botulinum toxin type A (BoNT-A) for the spasticity of the lower-limb post-stroke on gait and posture control.MethodsA total of 46 patients with hemiplegia gait were randomly divided into the experimental group (23 patients) and the control group (23 patients). In patients in the experimental group received injections of BoNT-A by electrical stimulation-guided. At the same time, patients of the two groups received routine physical therapy. Gait analysis, plantar pressure analysis, lower-limb Fugl–Meyer assessment (L-FMA), 10 meter walking test (10MWT), timed “Up and Go” test (TUGT), and modified Ashworth Scale assess (MAS) of the lower limbs were performed at 0, 1, 4, and 12 weeks after treatment.ResultsAt 1, 4, and 12 weeks after treatment, the L-FMA, stride length, speed, and TUGT significantly improved than 0 week in both groups. The L-FMA and peak of forefoot pressure, and MAS results in the experimental group were better than those in the control group at 4 and 12 weeks. The TUGT, speed, and stride length in experimental group was significantly shortened than that in control group at 1, 4, and 12 weeks.ConclusionBotulinum toxin type A injection can improve motor functions of the lower limb, gait, spasticity, forefoot pressure, and posture control of patients after stroke.https://www.frontiersin.org/articles/10.3389/fnins.2022.1107688/fullstrokebotulinum toxin Agaitspasticityposture control |
| spellingShingle | Hui-xian Yu Si-hao Liu Zhao-xia Wang Chang-bin Liu Pei Dai Da-wei Zang Efficacy on gait and posture control after botulinum toxin A injection for lower-limb spasticity treatment after stroke: A randomized controlled trial Frontiers in Neuroscience stroke botulinum toxin A gait spasticity posture control |
| title | Efficacy on gait and posture control after botulinum toxin A injection for lower-limb spasticity treatment after stroke: A randomized controlled trial |
| title_full | Efficacy on gait and posture control after botulinum toxin A injection for lower-limb spasticity treatment after stroke: A randomized controlled trial |
| title_fullStr | Efficacy on gait and posture control after botulinum toxin A injection for lower-limb spasticity treatment after stroke: A randomized controlled trial |
| title_full_unstemmed | Efficacy on gait and posture control after botulinum toxin A injection for lower-limb spasticity treatment after stroke: A randomized controlled trial |
| title_short | Efficacy on gait and posture control after botulinum toxin A injection for lower-limb spasticity treatment after stroke: A randomized controlled trial |
| title_sort | efficacy on gait and posture control after botulinum toxin a injection for lower limb spasticity treatment after stroke a randomized controlled trial |
| topic | stroke botulinum toxin A gait spasticity posture control |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2022.1107688/full |
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