Novel miR-b2122 regulates several ALS-related RNA-binding proteins
Abstract Common pathological features of amyotrophic lateral sclerosis (ALS) include cytoplasmic aggregation of several RNA-binding proteins. Out of these RNA-binding proteins, TDP-43, FUS/TLS and RGNEF have been shown to co-aggregate with one another within motor neurons of sporadic ALS (sALS) pati...
Main Authors: | Zachary C. E. Hawley, Danae Campos-Melo, Michael J. Strong |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13041-017-0326-7 |
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