A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing
A review of the human developmental neuroimaging literature that investigates outcomes following exposure to psychosocial adversity is presented with a focus on two subcortical structures – the hippocampus and the amygdala. Throughout this review, we discuss how a consideration of developm...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2010-01-01
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| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/neuro.09.068.2009/full |
| _version_ | 1811325928761982976 |
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| author | Nim Tottenham Margaret A Sheridan |
| author_facet | Nim Tottenham Margaret A Sheridan |
| author_sort | Nim Tottenham |
| collection | DOAJ |
| description | A review of the human developmental neuroimaging literature that investigates outcomes following exposure to psychosocial adversity is presented with a focus on two subcortical structures – the hippocampus and the amygdala. Throughout this review, we discuss how a consideration of developmental timing of adverse experiences and age at measurement might provide insight into the seemingly discrepant findings across studies. We use findings from animal studies to suggest some mechanisms through which timing of experiences may result in differences across time and studies. The literature suggests that early life may be a time of heightened susceptibility to environmental stressors, but that expression of these effects will vary by age at measurement. |
| first_indexed | 2024-04-13T14:41:44Z |
| format | Article |
| id | doaj.art-bfcf60a29bdf44b39d65f6cd6b28a644 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-04-13T14:41:44Z |
| publishDate | 2010-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-bfcf60a29bdf44b39d65f6cd6b28a6442022-12-22T02:42:53ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612010-01-01310.3389/neuro.09.068.20091019A review of adversity, the amygdala and the hippocampus: a consideration of developmental timingNim Tottenham0Margaret A Sheridan1UCLAHarvard UniversityA review of the human developmental neuroimaging literature that investigates outcomes following exposure to psychosocial adversity is presented with a focus on two subcortical structures – the hippocampus and the amygdala. Throughout this review, we discuss how a consideration of developmental timing of adverse experiences and age at measurement might provide insight into the seemingly discrepant findings across studies. We use findings from animal studies to suggest some mechanisms through which timing of experiences may result in differences across time and studies. The literature suggests that early life may be a time of heightened susceptibility to environmental stressors, but that expression of these effects will vary by age at measurement.http://journal.frontiersin.org/Journal/10.3389/neuro.09.068.2009/fullHippocampusdevelopmenthumanstressadversityExpression |
| spellingShingle | Nim Tottenham Margaret A Sheridan A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing Frontiers in Human Neuroscience Hippocampus development human stress adversity Expression |
| title | A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing |
| title_full | A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing |
| title_fullStr | A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing |
| title_full_unstemmed | A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing |
| title_short | A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing |
| title_sort | review of adversity the amygdala and the hippocampus a consideration of developmental timing |
| topic | Hippocampus development human stress adversity Expression |
| url | http://journal.frontiersin.org/Journal/10.3389/neuro.09.068.2009/full |
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