Liposome-Encapsulated Berberine Alleviates Liver Injury in Type 2 Diabetes via Promoting AMPK/mTOR-Mediated Autophagy and Reducing ER Stress: Morphometric and Immunohistochemical Scoring

Liposome-Encapsulated Berberine Alleviates Liver Injury in Type 2 Diabetes via Promoting AMPK/mTOR-Mediated Autophagy and Reducing ER Stress: Morphometric and Immunohistochemical Scoring

In the advanced stages of type 2 diabetes mellitus (T2DM), diabetic liver damage is a common complication that can devastate a patient’s quality of life. The present study investigated the ability of liposomal berberine (Lip-BBR) to aid in ameliorating hepatic damage and steatosis, insulin homeostas...

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Bibliographic Details
Main Authors: Safaa I. Khater, Taghreed N. Almanaa, Doaa M. Abdel Fattah, Tarek Khamis, Mona M. Seif, Naief Dahran, Leena S. Alqahtani, Mohamed M. M. Metwally, Mahmoud Mostafa, Raghad A. Albedair, Azza I. Helal, Manal Alosaimi, Amany Abdel-Rahman Mohamed
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Antioxidants
Subjects:
autophagy
AMPK/mTOR
Bclin-1
liposomal berberine
ER stress
type 2 diabetes
Online Access:https://www.mdpi.com/2076-3921/12/6/1220

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