Evaluation of the Efficacy of the <named-content content-type="genus-species">Brucella canis</named-content> RM6/66 Δ<italic toggle="yes">vjbR</italic> Vaccine Candidate for Protection against <named-content content-type="genus-species">B. canis</named-content> Infection in Mice

Evaluation of the Efficacy of the <named-content content-type="genus-species">Brucella canis</named-content> RM6/66 Δ<italic toggle="yes">vjbR</italic> Vaccine Candidate for Protection against <named-content content-type="genus-species">B. canis</named-content> Infection in Mice

ABSTRACT Brucella canis is a Gram-negative, facultative intracellular bacterium and the causative agent of canine brucellosis, a highly contagious disease of dogs that can be transmitted to humans. Unfortunately, no vaccine is available to prevent infection. We recently characterized the kinetics of...

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Bibliographic Details
Main Authors: Lauren W. Stranahan, Sankar P. Chaki, Daniel G. Garcia-Gonzalez, Omar H. Khalaf, Angela M. Arenas-Gamboa
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mSphere
Subjects:
Brucella canis
brucellosis
modified live vaccine
mouse model
vaccine
vaccine efficacy
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00172-20

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