The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis
Summary: Recent reports have shown the critical role of the mitochondrial antiviral signaling (MAVS) protein in virus-induced apoptosis, but the involvement of MAVS in tumorigenesis is still poorly understood. Herein, we report that MAVS is a key regulator of p53 activation and is critical for prote...
Main Authors: | Wanchuan Zhang, Jing Gong, Huan Yang, Luming Wan, Yumeng Peng, Xiaolin Wang, Jin Sun, Feng Li, Yunqi Geng, Dongyu Li, Ning Liu, Gangwu Mei, Yuan Cao, Qiulin Yan, Huilong Li, Yanhong Zhang, Xiang He, Qiaozhi Zhang, Rui Zhang, Feixiang Wu, Hui Zhong, Congwen Wei |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719317085 |
Similar Items
-
TP53BP2: Roles in suppressing tumorigenesis and therapeutic opportunities
by: Yunfei Huo, et al.
Published: (2023-09-01) -
The RNA binding protein RALY suppresses p53 activity and promotes lung tumorigenesis
by: Hao Hu, et al.
Published: (2023-04-01) -
MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis
by: Akaogi Kensuke, et al.
Published: (2013-02-01) -
Denervation suppresses gastric tumorigenesis
by: Zhao, Chun-Mei, et al.
Published: (2015) -
Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis
by: Xiufang Xiong, et al.
Published: (2014-08-01)