A pharmacokinetic study on twenty-one compounds in rat plasma by integrating UPLC-QQQ-MS/MS with GC-MS after oral administration of Suxiao Jiuxin pill

A pharmacokinetic study on twenty-one compounds in rat plasma by integrating UPLC-QQQ-MS/MS with GC-MS after oral administration of Suxiao Jiuxin pill

Suxiao Jiuxin pill (SX) was a commonly used traditional Chinese medical preparation for treating acute myocardial infarction. However, fewer studies have been reported for comprehensively investigating the pharmacokinetic of the non-volatile and volatile chemical constituents in SX. For current stud...

Full description

Bibliographic Details
Main Authors:	Ye Shang, Minglei Ge, Peng Zhao, Tiantian Wu, Shujie Wei, Hong Zhou, Yongping Jiang, Dandan Shang, Jun Wang, Tong Geng, Jun He
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Series:	Arabian Journal of Chemistry
Subjects:	Suxiao Jiuxin pill Pharmacokinetic UPLC-QQQ-MS/MS GC-MS
Online Access:	http://www.sciencedirect.com/science/article/pii/S1878535223008596

Similar Items

Suxiao Jiuxin Pill attenuates acute myocardial ischemia via regulation of coronary artery tone
by: Sa Li, et al.
Published: (2023-05-01)

Suxiao Jiuxin Pill alleviates myocardial ischemia–reperfusion injury through the ALKBH5/GSK3β/mTOR pathway
by: Yiping Li, et al.
Published: (2023-03-01)

Efficacy and safety of Suxiao Jiuxin Pill in the treatment of stable angina (Qi stagnation and blood stasis syndrome): study protocol of a randomized, double-blind, placebo-controlled, multi-center clinical trial
by: Xiaofen Ruan, et al.
Published: (2021-07-01)

Quality Evaluation of Tricholoma matsutake Based on the Nucleic Acid Compounds by UPLC-TOF/MS and UPLC-QqQ/MS
by: Ying Xue, et al.
Published: (2018-12-01)

Metabolite Profiling of 14 Wuyi Rock Tea Cultivars Using UPLC-QTOF MS and UPLC-QqQ MS Combined with Chemometrics
by: Si Chen, et al.
Published: (2018-01-01)

Profiling Phenolic Composition in Pomegranate Peel From Nine Selected Cultivars Using UHPLC-QTOF-MS and UPLC-QQQ-MS
by: Guowei Man, et al.
Published: (2022-01-01)

Simultaneous determination of twenty-nine active compounds in fuzhengjiedu granules by HPLC-QQQ-MS/MS
by: Yu-Feng Huang, et al.
Published: (2023-02-01)

Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS
by: Chenghuan Yan, et al.
Published: (2023-07-01)

A Comprehensive and Rapid Quality Evaluation Method of Traditional Chinese Medicine Decoction by Integrating UPLC-QTOF-MS and UFLC-QQQ-MS and Its Application
by: Yinfang Chen, et al.
Published: (2019-01-01)

Simultaneous Determination of Thirteen Q-Markers in Raw and Processed <i>Tussilago farfara</i> L. by UPLC-QQQ-MS/MS Coupled with Chemometrics
by: Liu Yang, et al.
Published: (2019-02-01)

UPLC-QqQ-MS/MS-based Quantitative Analysis on Bile Acid in Hyperthyroidism Rats to Explore the Effects of Ginseng Herbs
by: LIU Lin-lin, et al.
Published: (2023-07-01)

Diclofenac Concentrations in Post-Mortem Specimens—Distribution, Case Reports, and Validated Method (UHPLC-QqQ-MS/MS) for Its Determination
by: Paweł Szpot, et al.
Published: (2022-07-01)

The Integrated Study on the Chemical Profiling to Explore the Constituents and Mechanism of Traditional Chinese Medicine Preparation Huatuo Jiuxin Pills Based on UPLC-Q-TOF/MSE and Network Pharmacology
by: Yulong Zhu, et al.
Published: (2022-03-01)

Determination of Aflatoxins in Grains by QuEChERS-UPLC-MS/MS
by: WU Qin-yan, et al.
Published: (2024-03-01)

Quantitative Analysis of Eight Compounds in Traditional Korean Medicine, Gongjindan Using HPLC, UPLC–MS/MS, and GC–MS/MS Systems
by: Chang-Seob Seo, et al.
Published: (2023-03-01)

Detection of clobazam and its metabolites in urine during poisoning using HPLC-QqQ-MS/MS
by: Alla A. Volkova, et al.
Published: (2022-12-01)

Absolute bioavailability, dose proportionality, and tissue distribution of rotundic acid in rats based on validated LC-QqQ-MS/MS method
by: Haihua Shang, et al.
Published: (2022-04-01)

Multi-Residue Analysis of Pesticide Residues in Crude Pollens by UPLC-MS/MS
by: Zhou Tong, et al.
Published: (2016-12-01)

Simultaneous quantification of bioactive components in Chinese herbal spirits by ultra-high performance liquid chromatography coupled to triple-quadrupole mass spectrometry (UHPLC–QQQ–MS/MS)
by: Yan Hu, et al.
Published: (2021-03-01)

Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS
by: Vanessa de Jesus Gaffney, et al.
Published: (2014-01-01)

Validation of UPLC-MS/MS Method for Determination of Urinary Lactulose/Mannitol
by: Jacopo Gervasoni, et al.
Published: (2018-10-01)

Quantification of Nineteen Bioactive Components in the Ancient Classical Chinese Medicine Formula of Wen-Dan Decoction and Its Commercial Preparations by UHPLC-QQQ-MS/MS
by: Bing Zhang, et al.
Published: (2019-05-01)

Comparative Analysis of Hydrophilic Ingredients in Toad Skin and Toad Venom Using the UHPLC-HR-MS/MS and UPLC-QqQ-MS/MS Methods Together with the Anti-Inflammatory Evaluation of Indolealkylamines
by: Yu Zhang, et al.
Published: (2018-12-01)

SPE–UPLC–MS/MS for Determination of 36 Monomers of Alkylphenol Ethoxylates in Tea
by: Qin Lin, et al.
Published: (2023-04-01)

Determination of oleandrin and adynerin in rat plasma by UPLC–MS/MS and their pharmacokinetic study
by: Meiling Zhang, et al.
Published: (2022-12-01)

UPLC-MS/MS quantification of quercetin in plasma and urine following parenteral administration
by: Igor A. Zupanets, et al.
Published: (2019-01-01)

Development of an UPLC-MS/MS method for quantitative analysis of abexinostat levels in rat plasma and application of pharmacokinetics
by: Yige Yu, et al.
Published: (2024-02-01)

UPLC–MS/MS for the determination of azilsartan in beagle dog plasma and its application in a pharmacokinetics study
by: Cheng Gong, et al.
Published: (2015-06-01)

Establishment of a sensitive UPLC-MS/MS method to quantify safinamide in rat plasma
by: Ying Wang, et al.
Published: (2023-08-01)

Establishment and validation of a UPLC-MS/MS bioassay for the quantification of infigratinib in rat plasma
by: Xuegu Xu, et al.
Published: (2022-07-01)

Validation of Pesticides Multi-Residual Testing Method on Nutmeg by Using UPLC-MS/MS
by: Bayu Refindra Fitriadi
Published: (2021-12-01)

Development of UPLC-MS/MS Method for Studying the Pharmacokinetic Interaction Between Dasatinib and Posaconazole in Rats
by: Yang S, et al.
Published: (2021-05-01)

An Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC–MS/MS) Method for Qualifying DAPB in Rat Plasma and Application to Pharmacokinetic Studies
by: Bei Qin, et al.
Published: (2024-01-01)

Simultaneous Determination of Parecoxib and Its Metabolite Valdecoxib Concentrations in Beagle Plasma by UPLC-MS/MS and Application for Pharmacokinetics Study
by: Li S, et al.
Published: (2020-03-01)

Insight into the mechanisms of therapeutic hypothermia for asphyxia cardiac arrest using a comprehensive approach of GC-MS/MS and UPLC-Q-TOF-MS/MS based on serum metabolomics
by: Yiyuan Zhang, et al.
Published: (2023-06-01)

Development of a Proton-Enhanced ESI UPLC-MS/MS Method for the Determination of Tetrodotoxin
by: Tong Li, et al.
Published: (2022-12-01)

Development of an UPLC-MS/MS Method for Quantitative Analysis of Clotrimazole in Human Plasma Samples
by: Lucia Lisi, et al.
Published: (2020-11-01)

Residue Depletion of Imidocarb in Bovine Tissues by UPLC-MS/MS
by: Yaoxin Tang, et al.
Published: (2022-12-01)

Comparative Pharmacokinetics of Cinobufacini Capsule and Injection by UPLC-MS/MS
by: Ming Li, et al.
Published: (2022-07-01)

Pharmacokinetics, Bioavailability, and Tissue Distribution of the Kirsten Rat Sarcoma Inhibitor Adagrasib in Rats Using UPLC-MS/MS
by: Lei P, et al.
Published: (2024-01-01)