RoMIA: a framework for creating Robust Medical Imaging AI models for chest radiographs

Artificial Intelligence (AI) methods, particularly Deep Neural Networks (DNNs), have shown great promise in a range of medical imaging tasks. However, the susceptibility of DNNs to producing erroneous outputs under the presence of input noise and variations is of great concern and one of the largest...

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Main Authors: Aditi Anand, Sarada Krithivasan, Kaushik Roy
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Radiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fradi.2023.1274273/full
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author Aditi Anand
Sarada Krithivasan
Kaushik Roy
author_facet Aditi Anand
Sarada Krithivasan
Kaushik Roy
author_sort Aditi Anand
collection DOAJ
description Artificial Intelligence (AI) methods, particularly Deep Neural Networks (DNNs), have shown great promise in a range of medical imaging tasks. However, the susceptibility of DNNs to producing erroneous outputs under the presence of input noise and variations is of great concern and one of the largest challenges to their adoption in medical settings. Towards addressing this challenge, we explore the robustness of DNNs trained for chest radiograph classification under a range of perturbations reflective of clinical settings. We propose RoMIA, a framework for the creation of Robust Medical Imaging AI models. RoMIA adds three key steps to the model training and deployment flow: (i) Noise-added training, wherein a part of the training data is synthetically transformed to represent common noise sources, (ii) Fine-tuning with input mixing, in which the model is refined with inputs formed by mixing data from the original training set with a small number of images from a different source, and (iii) DCT-based denoising, which removes a fraction of high-frequency components of each image before applying the model to classify it. We applied RoMIA to create six different robust models for classifying chest radiographs using the CheXpert dataset. We evaluated the models on the CheXphoto dataset, which consists of naturally and synthetically perturbed images intended to evaluate robustness. Models produced by RoMIA show 3%–5% improvement in robust accuracy, which corresponds to an average reduction of 22.6% in misclassifications. These results suggest that RoMIA can be a useful step towards enabling the adoption of AI models in medical imaging applications.
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spelling doaj.art-bfdd15c97ff94ba18b0d4f4bc968798b2024-01-08T05:53:05ZengFrontiers Media S.A.Frontiers in Radiology2673-87402024-01-01310.3389/fradi.2023.12742731274273RoMIA: a framework for creating Robust Medical Imaging AI models for chest radiographsAditi AnandSarada KrithivasanKaushik RoyArtificial Intelligence (AI) methods, particularly Deep Neural Networks (DNNs), have shown great promise in a range of medical imaging tasks. However, the susceptibility of DNNs to producing erroneous outputs under the presence of input noise and variations is of great concern and one of the largest challenges to their adoption in medical settings. Towards addressing this challenge, we explore the robustness of DNNs trained for chest radiograph classification under a range of perturbations reflective of clinical settings. We propose RoMIA, a framework for the creation of Robust Medical Imaging AI models. RoMIA adds three key steps to the model training and deployment flow: (i) Noise-added training, wherein a part of the training data is synthetically transformed to represent common noise sources, (ii) Fine-tuning with input mixing, in which the model is refined with inputs formed by mixing data from the original training set with a small number of images from a different source, and (iii) DCT-based denoising, which removes a fraction of high-frequency components of each image before applying the model to classify it. We applied RoMIA to create six different robust models for classifying chest radiographs using the CheXpert dataset. We evaluated the models on the CheXphoto dataset, which consists of naturally and synthetically perturbed images intended to evaluate robustness. Models produced by RoMIA show 3%–5% improvement in robust accuracy, which corresponds to an average reduction of 22.6% in misclassifications. These results suggest that RoMIA can be a useful step towards enabling the adoption of AI models in medical imaging applications.https://www.frontiersin.org/articles/10.3389/fradi.2023.1274273/fullmedical imagingartificial intelligenceartificial neural networksrobustnessradiologychest radiographs
spellingShingle Aditi Anand
Sarada Krithivasan
Kaushik Roy
RoMIA: a framework for creating Robust Medical Imaging AI models for chest radiographs
Frontiers in Radiology
medical imaging
artificial intelligence
artificial neural networks
robustness
radiology
chest radiographs
title RoMIA: a framework for creating Robust Medical Imaging AI models for chest radiographs
title_full RoMIA: a framework for creating Robust Medical Imaging AI models for chest radiographs
title_fullStr RoMIA: a framework for creating Robust Medical Imaging AI models for chest radiographs
title_full_unstemmed RoMIA: a framework for creating Robust Medical Imaging AI models for chest radiographs
title_short RoMIA: a framework for creating Robust Medical Imaging AI models for chest radiographs
title_sort romia a framework for creating robust medical imaging ai models for chest radiographs
topic medical imaging
artificial intelligence
artificial neural networks
robustness
radiology
chest radiographs
url https://www.frontiersin.org/articles/10.3389/fradi.2023.1274273/full
work_keys_str_mv AT aditianand romiaaframeworkforcreatingrobustmedicalimagingaimodelsforchestradiographs
AT saradakrithivasan romiaaframeworkforcreatingrobustmedicalimagingaimodelsforchestradiographs
AT kaushikroy romiaaframeworkforcreatingrobustmedicalimagingaimodelsforchestradiographs