Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s Disease
ObjectivesTo compare the sensitivity of identification of penile plaques in the erect and flaccid penises by ultrasound in patients with Peyronie’s disease (PD).Materials and MethodsA total of 75 PD patients were screened by palpation and ultrasonography for penile lesions in both flaccid and erect...
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Frontiers Media S.A.
2019-04-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2019.00312/full |
| _version_ | 1818272289225965568 |
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| author | Yu Liu Dequan Zheng Xiaolin Liu Xiaohong Shi Shengchun Shu Jinbing Li |
| author_facet | Yu Liu Dequan Zheng Xiaolin Liu Xiaohong Shi Shengchun Shu Jinbing Li |
| author_sort | Yu Liu |
| collection | DOAJ |
| description | ObjectivesTo compare the sensitivity of identification of penile plaques in the erect and flaccid penises by ultrasound in patients with Peyronie’s disease (PD).Materials and MethodsA total of 75 PD patients were screened by palpation and ultrasonography for penile lesions in both flaccid and erect penises induced by prostaglandin E1 (PG-1) injection.ResultsA total of 138 lesions were identified by ultrasound in the erect penises induced by injection of PG-1. However, only 74.6% of the lesions (103) were detectable by the palpation of the flaccid penises, and 84.1% (116) by ultrasound of the flaccid penises. The ultrasound confirmed 99 of the palpated lesions in the flaccid penises. The detection rate of lesions in drug-induced erect penises by ultrasound was significantly higher than those in the flaccid penises by the ultrasound (P < 0.01) or palpation (P < 0.0005) The type of penile lesions identified by ultrasonography included tunical thickening, calcifications, septal fibrosis, and intracavernosal fibrosis. The ratios of these lesions confirmed by ultrasound were 52.6, 33.6, 6.0, and 7.8%, respectively, in the flaccid penises, and 55.8, 28.3, 8.7, and 7.2%, respectively, in the erect penises.ConclusionDrug-induced erection can be used in suspicious PD patients when penile lesion is not identified by palpation or ultrasound in the flaccid penis. |
| first_indexed | 2024-12-12T21:39:42Z |
| format | Article |
| id | doaj.art-bfdd978de6804c13bb91a40c7082a41c |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-12T21:39:42Z |
| publishDate | 2019-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-bfdd978de6804c13bb91a40c7082a41c2022-12-22T00:11:05ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122019-04-011010.3389/fphar.2019.00312445096Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s DiseaseYu Liu0Dequan Zheng1Xiaolin Liu2Xiaohong Shi3Shengchun Shu4Jinbing Li5Department of Ultrasonography, Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou, ChinaAndrology Center, Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou, ChinaDepartment of Ultrasonography, Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou, ChinaDepartment of Ultrasonography, Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou, ChinaDepartment of Ultrasonography, Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou, ChinaDepartment of Ultrasonography, Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou, ChinaObjectivesTo compare the sensitivity of identification of penile plaques in the erect and flaccid penises by ultrasound in patients with Peyronie’s disease (PD).Materials and MethodsA total of 75 PD patients were screened by palpation and ultrasonography for penile lesions in both flaccid and erect penises induced by prostaglandin E1 (PG-1) injection.ResultsA total of 138 lesions were identified by ultrasound in the erect penises induced by injection of PG-1. However, only 74.6% of the lesions (103) were detectable by the palpation of the flaccid penises, and 84.1% (116) by ultrasound of the flaccid penises. The ultrasound confirmed 99 of the palpated lesions in the flaccid penises. The detection rate of lesions in drug-induced erect penises by ultrasound was significantly higher than those in the flaccid penises by the ultrasound (P < 0.01) or palpation (P < 0.0005) The type of penile lesions identified by ultrasonography included tunical thickening, calcifications, septal fibrosis, and intracavernosal fibrosis. The ratios of these lesions confirmed by ultrasound were 52.6, 33.6, 6.0, and 7.8%, respectively, in the flaccid penises, and 55.8, 28.3, 8.7, and 7.2%, respectively, in the erect penises.ConclusionDrug-induced erection can be used in suspicious PD patients when penile lesion is not identified by palpation or ultrasound in the flaccid penis.https://www.frontiersin.org/article/10.3389/fphar.2019.00312/fullPeyronie’s diseaseultrasoundpenispalpationlesion identification |
| spellingShingle | Yu Liu Dequan Zheng Xiaolin Liu Xiaohong Shi Shengchun Shu Jinbing Li Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s Disease Frontiers in Pharmacology Peyronie’s disease ultrasound penis palpation lesion identification |
| title | Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s Disease |
| title_full | Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s Disease |
| title_fullStr | Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s Disease |
| title_full_unstemmed | Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s Disease |
| title_short | Ultrasound on Erect Penis Improves Plaque Identification in Patients With Peyronie’s Disease |
| title_sort | ultrasound on erect penis improves plaque identification in patients with peyronie s disease |
| topic | Peyronie’s disease ultrasound penis palpation lesion identification |
| url | https://www.frontiersin.org/article/10.3389/fphar.2019.00312/full |
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