Aspectos neuropsicológicos do transtorno obsessivo-compulsivo

<abstract language="eng">Neuropsychology is contributing to elucidate the nature of brain dysfunction associated with obsessive-compulsive disorder (OCD). Neuropsychological studies of individuals with subclinical and clinical obsessive-compulsive symptoms are reviewed here. It was o...

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Yazar: Leonardo Fontenelle
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Associação Brasileira de Psiquiatria (ABP) 2001-10-01
Seri Bilgileri:Brazilian Journal of Psychiatry
Konular:
Online Erişim:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462001000600009
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author Leonardo Fontenelle
author_facet Leonardo Fontenelle
author_sort Leonardo Fontenelle
collection DOAJ
description <abstract language="eng">Neuropsychology is contributing to elucidate the nature of brain dysfunction associated with obsessive-compulsive disorder (OCD). Neuropsychological studies of individuals with subclinical and clinical obsessive-compulsive symptoms are reviewed here. It was observed that OCD patients may display impaired "reality monitoring", memory for actions, non-verbal memory, visuo-spatial abilities, and executive functions. Some specific neuropsychological findings are associated with different clinical characteristics such as gender, duration of disease, severity of symptoms, and response to drug treatment. Comparative studies suggest that the neuropsychological dysfunction associated with OCD is significantly different from that seen in major depressive disorder or schizophrenia. However, many similarities were observed between patients with OCD and patients with social phobia, body dysmorphic disorder, and trichotillomania. Furthermore, studies suggest that certain neurochemical abnormalities may underlie particular neuropsychological dysfunctions found in OCD. Despite many heterogeneous results, the reviewed data seems to support the pathophysiological theory centered in the dysfunction of the fronto-striatal circuits in OCD.
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spelling doaj.art-bfddf89f13fd4a48897b6d1c85c2d7242022-12-22T03:48:48ZengAssociação Brasileira de Psiquiatria (ABP)Brazilian Journal of Psychiatry1516-44461809-452X2001-10-0123273010.1590/S1516-44462001000600009Aspectos neuropsicológicos do transtorno obsessivo-compulsivoLeonardo Fontenelle<abstract language="eng">Neuropsychology is contributing to elucidate the nature of brain dysfunction associated with obsessive-compulsive disorder (OCD). Neuropsychological studies of individuals with subclinical and clinical obsessive-compulsive symptoms are reviewed here. It was observed that OCD patients may display impaired "reality monitoring", memory for actions, non-verbal memory, visuo-spatial abilities, and executive functions. Some specific neuropsychological findings are associated with different clinical characteristics such as gender, duration of disease, severity of symptoms, and response to drug treatment. Comparative studies suggest that the neuropsychological dysfunction associated with OCD is significantly different from that seen in major depressive disorder or schizophrenia. However, many similarities were observed between patients with OCD and patients with social phobia, body dysmorphic disorder, and trichotillomania. Furthermore, studies suggest that certain neurochemical abnormalities may underlie particular neuropsychological dysfunctions found in OCD. Despite many heterogeneous results, the reviewed data seems to support the pathophysiological theory centered in the dysfunction of the fronto-striatal circuits in OCD.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462001000600009Obsessive-compulsive disorderNeuropsychologyPrefrontal cortexBasal ganglia
spellingShingle Leonardo Fontenelle
Aspectos neuropsicológicos do transtorno obsessivo-compulsivo
Brazilian Journal of Psychiatry
Obsessive-compulsive disorder
Neuropsychology
Prefrontal cortex
Basal ganglia
title Aspectos neuropsicológicos do transtorno obsessivo-compulsivo
title_full Aspectos neuropsicológicos do transtorno obsessivo-compulsivo
title_fullStr Aspectos neuropsicológicos do transtorno obsessivo-compulsivo
title_full_unstemmed Aspectos neuropsicológicos do transtorno obsessivo-compulsivo
title_short Aspectos neuropsicológicos do transtorno obsessivo-compulsivo
title_sort aspectos neuropsicologicos do transtorno obsessivo compulsivo
topic Obsessive-compulsive disorder
Neuropsychology
Prefrontal cortex
Basal ganglia
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462001000600009
work_keys_str_mv AT leonardofontenelle aspectosneuropsicologicosdotranstornoobsessivocompulsivo